依托咪酯联合丙泊酚静脉麻醉用于幽门下超声内镜检查的临床效果  

Clinical effects of intravenous anesthesia with etomidate plus propofol for subpyloric endoscopic ultrasonography

作　　者：吴超双[1] 孟波[1] 任海珍[2] 

机构地区：[1]宁波市第二医院麻醉科,浙江省宁波市315010 [2]宁波市第二医院内镜中心,浙江省宁波市315010

出　　处：《世界华人消化杂志》2017年第15期1405-1409,共5页World Chinese Journal of Digestology

摘　　要：目的观察依托咪酯联合丙泊酚静脉麻醉用于幽门下超声内镜(endoscopic ultrasonography,EUS)检查的临床效果.方法选取择期行幽门下EUS检查的患者60例,随机数字表法分为3组:依托咪酯组(E组)、依托咪酯联合丙泊酚组(EP组)和丙泊酚组(P组),记录3组患者操作过程中生命体征的变化、检查时间和苏醒时间,以及麻醉相关不良反应发生情况.结果 3组患者麻醉起效时间、检查时间及术后苏醒时间均无显著差异;E组和P组在检查过程中均出现明显的循环波动,E组有7例发生肌阵挛且总不良反应为15例,均较其他2组明显增加,差异有统计学意义(P<0.05).结论依托咪酯联合丙泊酚静脉麻醉能安全有效地应用于幽门下EUS检查,且不良反应更少,值得临床推广.AIM To investigate the clinical effects of intravenous anesthesia with etomidate plus propofol for deep sedation during subpyloric endoscopic ultrasonography （EUS）. We recruited 60 patients who would undergo subpyloric EUS examination. They were randomly allocated into three groups to receive intravenous etomidate alone （group E, n = 20）, intravenous propofol alone （group P, n = 20） and etomiclate combined with propofol （group EP, n = 20）, respectively. The change of patients＇ vital signs, examination duration, time to awakening, and adverse effects were observed. RES llL TS There was no significant difference in the onset time of anesthesia, examination duration or time to awakening among all groups （P 〉 0.05）. There was a significant circulatory fluctuation in group E and group P. In group E, 7 cases had myoclonus and a total of 15 cases developed adverse effects, and the rates of myoclonus and overall adverse effects were significantly higher than those in the other two groups （P 〈 0.05）. Intravenous anesthesia with etomidate plus propofol can be safely and effectively applied to ubpyloric EUS with few adverse effects.

关 键 词：依托咪酯 丙泊酚 静脉麻醉 超声内镜 

分 类 号：R614[医药卫生—麻醉学]