单纯畸形精子症对宫腔内人工授精结局的影响  

Influence of isolated teratozoospermia on the pregnancy outcome of intrauterine insemination

作　　者：陆月红[1] 华凯[1] 夏舟岚[1] 陈惠娟[1] 马英英[1] 李红梅[1] 

机构地区：[1]绍兴市妇幼保健院生殖医学中心,浙江绍兴312000

出　　处：《中国性科学》2017年第6期149-152,共4页Chinese Journal of Human Sexuality

基　　金：浙江省自然科学基金资助项目(LY15H040001)

摘　　要：目的:研究单纯畸形精子症对宫腔内人工授精(IUI)结局的相关性。方法:回顾性分析2012年1月至2015年12月本院生殖医学中心行夫精IUI治疗的不孕不育患者189例,共行323个IUI周期,按照WHO第5版精子形态学分析方法分为(1)正常对照组,146个周期,(2)轻中度畸形精子症组,121个周期,(3)重度畸形精子症组,56个周期,以临床妊娠率与早期流产率等为指标,以评估畸形精子症对IUI结局的影响。结果:三组间临床妊娠率、早期流产率、早产率及活产率等均无显著性差异(P>0.05)。结论:不论轻中度或重度畸形精子症对IUI后临床妊娠率、早期流产率、早产率及活产率等均无明显影响。Objectives： To determine the influence of isolated teratozoospermia on the pregnancy outcomes of intrauterine insemination（IUI）. Methods： A total of 189 couple of 323 IUI cycles from January 2012 to December 2015 were retrospectively analyzed in the Center for Reproductive Medicine of Shaoxing Women and Children＇Hospital. According with the criteria of the fifth version of World Health Organization,patients were divided into three groups,normal control group（n = 146）,mild teratozoospermia group（n = 121） and sever teratozoospermia group（n = 56）. Clinical pregnancy rates,early miscarriage rates,premature delivery rate and live birth rate werecompared among these groups. Results： The clinical pregnancy rate,early miscarriage rate and premature delivery rate of mild teratozoospermia group, severe teratozoospermia group and normal control group were 18. 18%,13. 64%,15. 79%; 16. 07%,11. 11%,12. 50% and 17. 81%,7. 69%,13. 04%,respectively. The live birth rate for the above three groups were all 100%. There was no statistical difference in clinical pregnancy rate,early miscarriage rate,premature delivery rate and live birth rate among the three groups（P〉0. 05）. Conclusion： Both mild and severe isolated teratozoospermia has no influence on the clinical pregnancy rates,early miscarriage rates,premature delivery rate and live birth rate after IUI.

关 键 词：畸形精子症 人工授精 临床结局 

分 类 号：R698.2[医药卫生—泌尿科学]