氟苯尼考与泰乐菌素对常见猪呼吸道病原菌的联合药敏试验  

Susceptibility Sesting of the Combination of Florfenicol and Tylosin Against Some Pathogenic Bacteria of Porcine Respiratory

作　　者：马团祥 刘汉高 邱凯[1] 李先强[1,2] 

机构地区：[1]塔里木大学动物科学学院,新疆阿拉尔843300 [2]新疆生产建设兵团塔里木畜禽科技重点实验室,新疆阿拉尔843300

出　　处：《塔里木大学学报》2017年第2期28-31,共4页Journal of Tarim University

基　　金：国家自然科学基金项目(31660729);塔里木大学校长基金青年创新资金项目(TDZKQN201603)

摘　　要：参照美国临床实验室标准化研究所(CLSI)制定的微量肉汤稀释法,本试验研究了氟苯尼考与泰乐菌素对猪链球菌、副猪嗜血杆菌、猪胸膜肺炎放线杆菌以及多杀性巴氏杆菌4种常见猪呼吸道病原菌联合药敏试验中的相互作用。结果表明,氟苯尼考和泰乐菌素单独使用时对各菌的最低抑菌浓度(MIC)分别在1~8μg/m L和0.5~2μg/m L之间,二者联合后的部分抑菌指数(FIC)介于0.5~0.75之间,表现为相加作用或协同作用。This study was conducted on the sensitivity of the pathogenic Streptococcus suis, Haemophilus parasuis, Actinobacillus pleuropneumoniae and Pasteurella multocida to florfenicol in combined with tylosin in vitro by broth micro - dilution method, which recommended by Clinical And Laboratory Standards Institute （CLSI）. The results showed that the minimal inhibitory concentration （MIC） of florfenicol and tylosin against the bacteria were 1~8μg/m Land0.5~2μg/m L when single used, and the fractional inhib- itory concentration （FIC） of florfenicol combined with tylosin was O. 5 ~ O. 75, respectively. This study suggested that the combination of florfenicol and tylosin to the bacteria had an additive or synergistic effect.

关 键 词：氟苯尼考 泰乐菌素 猪呼吸道病原菌 联合药敏 

分 类 号：S859.1[农业科学—临床兽医学]