一株野生毛头鬼伞子实体对小鼠的亚急性毒性试验  

Evaluation of a Coprinus comatus Fruit Bodyfor Sub-acute Toxicityin Mice

作　　者：曹晋良 韩建荣[1] 

机构地区：[1]山西大学生命科学学院,山西太原030006

出　　处：《食用菌学报》2017年第2期71-74,共4页Acta Edulis Fungi

基　　金：山西省煤基重点科技攻关项目(FT2014-03-15)资助

摘　　要：以小鼠为受试动物评价一株野生毛头鬼伞(Coprinus comatus)菌株ZMM-3人工栽培子实体的食用安全性,结果在高、中、低(5000、500、50mg/kg·d)剂量组实验中小鼠全部健活,体征、体重、行为、外观、脏器系数、血液生理生化指标、脏器结构均无明显异常,表明供试毛头鬼伞子实体对小鼠没有亚急性毒性。Organ coefficients （lung, kidney, heart, spleen, liver）, hematological criteria and various biochemical parameters were monitored in mice administered 50, 500 and 5000 mg/kg · d of a powdered Coprinus comatus fruit body （designated ZMM-3） collected from the wild. No abnormal physical signs, changes in behavior, body weight, organ coefficients, and hematological and biochemical parameters were observed, indicating the absence of any obvious sub-acute toxicity.

关 键 词：野生毛头鬼伞 亚急性毒性 脏器结构 

分 类 号：S646[农业科学—蔬菜学]