中医周期疗法联合热敏灸治疗肝郁肾虚痰瘀型HPRL不孕疗效观察  

Curative Effect Observation of Chinese Medicine Periodic Therapy Combined with Thermalmoxibustion in Treating HPRL Infertility with Syndrome of Hepatic Stagnation and Kidney Insufficiency Merged Phlegm-Stasis

作　　者：段祖珍[1] 潘红燕[1] 杜昊[1] 俎丽[1] 张文艳[1] 官文娟[1] 

机构地区：[1]广州中医药大学附属宝安中医院,广东深圳518133

出　　处：《新中医》2017年第6期117-120,共4页New Chinese Medicine

基　　金：深圳市科技计划资助项目(JCYJ20140411135954555)

摘　　要：目的:观察中医周期疗法联合热敏灸治疗肝郁肾虚痰瘀型高催乳素血症(HPRL)不孕临床疗效。方法:将60例患者随机分成2组各30例,治疗组采用中医周期疗法联合热敏灸治疗,对照组用溴隐亭治疗。观察2组临床疗效和治疗前后卵巢功能变化、子宫内膜厚度、排卵率及妊娠率。结果:2组临床疗效治疗组治愈率66.7%,总有效率96.7%;对照组治愈率40.0%,总有效率93.3%;2组间治愈率比较,差异有统计学意义(P<0.05);2组间总有效率比较,差异无统计学意义(P>0.05)。治疗后,2组优势卵泡直径、内膜厚度均较治疗前增加,差异均有统计学意义(P<0.05);但治疗组增加更显著,差异有统计学意义(P<0.01)。2组排卵率、妊娠率比较,排卵率治疗组80.0%,对照组53.3%,2组排卵率比较,差异有统计学意义(P<0.05);妊娠率治疗组66.7%,对照组40.0%,2组妊娠率比较,差异有统计学意义(P<0.05)。治疗前后2组性激素各项指标变化情况比较,差异均有统计学意义(P<0.05);治疗组变化更明显,2组间比较,差异有统计学意义(P<0.01)。结论:中医周期疗法联合热敏灸治疗肝郁肾虚痰瘀型HPRL性不孕内外合治,切中病机,疗效确切,副作用小,对妊娠也基本无影响,可为HPRL性不孕患者提供一种新方法,值得应用。Objective：To observe the effect of Chinese medicine periodic therapy combined with thermalmoxibustion in treating hyperprolactinemia（HPRL） infertility with syndrome of hepatic stagnation and kidney insufficiency merged phlegm-stasis. Methods：Selected 60 patients and divided them into two groups being 30 cases in each. The treatment group was given Chinese medicine periodic therapy combined with thermalmoxibustion, and the control group was given bromocriptine. Observed clinical effect and change of ovarian function before and after treatment, endometrial thickness,pregnancy rate and ovulation rate of the two groups. Results：The clinical cure rate and total effective rate was 66.7% and96.7% in the treatment group respectively,and was 40.0% and 93.3% in the control group respectively. The difference of cure rate of the two groups was significant（P〈0.05）,but the difference of total effective rate of the two groups was not significant（P〈0.05）. After treatment, diameter of dominant follicle and intimal thickness of the two groups increased, the difference being significant（P〈0.05）, but the increase of the treatment group was more significant, the difference being significant（P〈0.01）. Ovulation rate was 80.0% and 53.3% in the treatment group and control group respectively, the difference being significant（P〈0.05）; Pregnancy rate was 66.7% and 40.0% in the treatment group and control group respectively,the difference being significant（P〈0.05）. Compared indexes of sex hormone of the two groups before and after treatment,the difference being significant（P〈0.05）;Change in the treatment group was more significant, the difference being significant（P〈0.01）. Conclusion： Chinese medicine periodic therapy combined with thermalmoxibustion has a good command of pathogenesis and has accurate curative effect,less adverse reaction and little impact on pregnancy in treating HPRL infertility,which is a new way worth of application.

关 键 词：高催乳素血症 不孕症 中医周期疗法 热敏灸 优势卵泡直径 内膜厚度 妊娠率 排卵率 

分 类 号：R711.6[医药卫生—妇产科学]