Serum thioredoxin activity:a promising biomarker for assessment of coronary stenosis severity in patients with coronary artery disease  

作　　者：Jinling Li Pei Wang Li Xiao Jianmin Yu Xianrui Kong Liangwei Zhong 

机构地区：[1]Medical School,University of Chinese Academy of Sciences [2]Beijing Key Laboratory of Immunology Regulation and Organ Transplantation,Basic Research Laboratory of Organ Transplant Institute,the 309th Hospital of the People's Liberation Army

出　　处：《Science Bulletin》2017年第11期752-754,共3页科学通报（英文版）

基　　金：supported by grants from National Natural Science Foundation of China(31170764,31470790);Science and Education Integration Project of University of Chinese Academy of Sciences(KJRH2015-008);Key Projects of Science and Technology Program by Beijing Municipal Education Commission(KZ201610025020)

摘　　要：Coronary artery disease(CAD)is one of the major death causes worldwide.Therapeutic methods may improve the progress of CAD.Thus,specific biomarkers are required for detecting coronary stenosis severity and monitoring therapy.Although spiral computed tomography(CT)angiography or coronary angiography may accurate detect coronary stenosis,the both techniquesCoronary artery disease （CAD） is one of the major death causes worldwide. Therapeutic methods may improve the progress of CAD. Thus, specific biomarkers are required for detecting coronary stenosis severity and monitoring therapy, Although spiral computed tomography （CT） angiography or coronary angiography may accurate detect coronary stenosis, the both techniques are expensive and not used as a ＂screening＂ test in the general population. The diagnostic ability of coronary angiography decreased in severe and complex lesions, especially for distal segments [1]. The diagnostic value of Coronary CT angiography is hampered by certain limitations [2]. Therefore, there is need for more convenient methods to predict coronary stenosis severity.

关 键 词：动脉狭窄 冠心病 生物标记物 蛋白活性 冠状动脉造影 冠状动脉疾病 患者 评价 

分 类 号：R541.4[医药卫生—心血管疾病]