氨溴索联合小剂量肝素雾化吸入治疗小儿重症肺炎疗效分析  

Curative Effect of Ammonia Bromine in Combination with Small Dose of Heparin Atomization Inhalation in the Treatment of Children with Severe Pneumonia

作　　者：崔利丹 金志鹏 王琪 成怡冰 王群思 

机构地区：[1]郑州儿童医院,河南郑州450000

出　　处：《药品评价》2017年第10期41-43,61,共4页Drug Evaluation

摘　　要：目的:探讨氨溴索联合小剂量肝素雾化吸入治疗小儿重症肺炎疗效,为氨溴索联合小剂量肝素雾化吸入治疗小儿重症肺炎的应用提供理论依据。方法:选取2014年11月—2016年11月在我院接受治疗的90例小儿重症肺炎患儿作为此次研究对象,给予患儿药物治疗,并根据药物的不同分为观察组与对照组,每组患儿45例,对照组患儿采用常规治疗,观察组患儿在对照组的基础上采用氨溴索联合小剂量肝素雾化吸入治疗,对两组患儿的症状和体征进行观察和记录,分析比较两组患儿临床症状消失时间情况、治疗效果情况。结果:观察组患儿气促、鼻翼煽动、三凹征、紫绀、肺部啰音相比于对照组时间明显更低,组间比较差异具有统计学意义(P<0.05);观察组患儿总有效率为91.11%相比于对照组的75.56%,观察组总有效率明显更高,组间比较差异具有统计学意义(P<0.05)。结论:氨溴索联合小剂量肝素雾化吸入治疗小儿重症肺炎疗效显著,患儿的各项症状和生活质量得到显著改善,不良反应发生率明显下降,治愈率和安全性明显上升,值得推广应用。Objective： to study the ammonia bromine line in combination with small dose of heparin atomization inhalation in the treatment of children with severe pneumonia curative effect, for ammonia bromine line in combination with small dose of heparin atomization inhalation application provide theoretical basis for the treatment of children with severe pneumonia. Methods： 90 cases of children with severe pneumonia in the hospital from November 2014-November 2016 were divided into observation group and control group, each group of children with 45 cases. Control group was with conventional therapy, observation group on the basis of the ammonia bromine in combination with small dose of heparin atomization inhalation therapy, to observe the signs and symptoms of two groups, and records, analysis and comparison of two groups of children with clinical symptoms disappear time, treatment effect were preformed. Results： Observation group was with shortness of breath, less nose incitement and purple compared with the control group（P〈0.05）; total effective rate of observation group was 91.11% vs. control group 75.56%, thus total effective observation group was obviously higher（P〈0.05）. Conclusion： The effect of ammonia bromine in combination with small dose of heparin atomization inhalation in the treatment of children with severe pneumonia is distinct. The patient＇s symptoms and quality of life improved significantly, with lower incidence of adverse reactions, the cure rate and safety rise obviously, thus is worth of popularization and application.

关 键 词：氨溴索 小剂量肝素 雾化吸入 小儿重症肺炎 疗效分析 

分 类 号：R725.6[医药卫生—儿科]