氧化应激对女性生殖系统的损伤作用  

The damage effect of oxidative stress on female reproductive system

作　　者：何欣[1] 王彤[1] 马延敏[1] 

机构地区：[1]首都医科大学附属北京妇产医院生殖医学中心,100026

出　　处：《中国优生与遗传杂志》2017年第6期1-2,104,共3页Chinese Journal of Birth Health & Heredity

基　　金：北京市卫生系统高层次卫生技术人才"科研骨干"(2014-3-076);首都医科大学基础-临床科研合作基金(15JL77)资助

摘　　要：研究表明,氧化应激可造成全身多个器官系统的损伤,包括男性生殖系统,然而,氧化应激对于女性生殖系统的损伤作用却缺乏研究。本文阐述了氧化应激与女性不孕症的相关性,并从卵巢细胞凋亡、卵巢衰老与炎症反应三方面综述了氧化应激对生殖系统损伤作用的机制。Recent years, oxidative stress research is gaining increasing attenuon, it has been Ioune mat oxidative stress can induce multiple organ damages, including male reproductive system. However, the research of the damage effect caused by oxidative stress is still limited. The article not only investigated the relation between oxidative stress and female infertility, but also demonstrated the mechanism of the damage effect from three aspects： ovarian ceils apoptosis, ovarian aging and inflammation. The article may provide new ideas to protect female reproductive system, maintain reproductive function and treat the infertility.

关 键 词：氧化应激 不孕症 凋亡 衰老 

分 类 号：R711[医药卫生—妇产科学]