正常卵巢反应人群中超长方案与长方案在IVF-ET中妊娠结局的比较研究  

Effect comparison of prolonged protocol and long protocol among the normal ovarian response patients in IVFET

作　　者：杜娟 包俊华 郝苗苗 

机构地区：[1]银川市妇幼保健院生殖医学中心,宁夏银川750001

出　　处：《中国优生与遗传杂志》2017年第6期110-112,共3页Chinese Journal of Birth Health & Heredity

摘　　要：目的比较正常卵巢反应人群中超长方案与长方案在体外受精/卵泡浆内单精子显微注射-胚胎移植(IVF/ICSI-ET)中妊娠结局的差异性。方法对本中心2015年1月至2015年12月行IVF/ICSI-ET的新鲜周期149例患者行回顾性研究,其中超长方案组44例,长方案组105例。结果超长方案组促性腺激素(Gonadotrophin,Gn)启动量及Gn总量较大,Gn启动日黄体生成素(LH)水平、促排卵第7日(S7)及人绒毛膜促性腺激素(HCG)注射日LH水平及雌二醇(E2)水平较低,差异具有统计学意义(P<0.05);超长方案组受精率和卵裂率较低,差异具有统计学意义(P<0.05);超长方案组种植率及临床妊娠率有升高的趋势,但差异无统计学意义(P>0.05)。结论在正常卵巢反应人群中,超长方案可能较长方案有更高的临床妊娠率,可作为这部分人群的首选方案。Objective： To compare the outcome of the normal ovarian response patients undergone IVF/ICSI-ET conducted with prolonged protocol and long protocol. Methods： The clinical data of 149 patients in fresh cycle undergone IVF/ICSI-ET in our center from January 2015 to December 2015 were analyzed, the patients were divided into prolonged protocol group （44 cases） and long protocol group （105cases） . Results： The initial and total dose of gonadotropin in prolonged protocol group were higher than long protocol group.LH on the starting day of ovulation induction, both E2 and LH on the seventh day of ovulation induction and the day of HCG, fertilization rate, oocyte cleavage rate in prolonged protocol group were lower than long protocol group. There were increasing tendency in implantation rate and clinical pregnancy rate in prolonged protocol group, but with no statistical significance. Conclusion： Among the normal ovarian response patients, clinical pregnancy rate in prolonged protocol may be higher than long protocol, It may become the preferable choice of the normal ovarian response patients.

关 键 词：超长方案 长方案 体外受精-胚胎移植 临床妊娠率 

分 类 号：R714.8[医药卫生—妇产科学]