基于灰色关联度法评价栀子药材质量  

Quality Evaluation of Gardeniae Fructus by Grey Incidence Degree Method

作　　者：龚雨虹 罗光明[1] 张风波[1] 袁源见 李波[1] 肖日传 谢晶[1] 张博文[1] 

机构地区：[1]江西中医药大学药学院,南昌330004

出　　处：《中国实验方剂学杂志》2017年第13期74-79,共6页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：国家公益性科研专项(201507002)

摘　　要：目的:依据灰色关联分析方法评价栀子药材质量。方法:收集20份不同产地栀子药材样品,测定其栀子苷,京尼平1-β-D-龙胆二糖苷,绿原酸,西红花苷-Ⅰ,京尼平苷酸,西红花苷-Ⅱ6种主要成分的含量,采用灰色关联度法,以定义的相对关联度为测度,构建栀子药材质量评价模型。结果:应用该方法建立了栀子药材商品的质量评价模型,收集栀子代表产区的20批栀子商品药材进行客观地评价,得到各评价单元序列的相对关联度在0.309 7~0.524 4,单元序列的相对关联度>0.450的样本有7批,这些批次样本的质量评价较高,其中1,2,7,12,19批样品质量排在前5,说明该样品产区的栀子质量相对较好,同时观察实际栀子商品药材质地,这与目前栀子商品规格划分标准(成熟程度、是否饱满和色泽深浅)情况相一致,充分说明了运用灰色关联分析结果与药材的实际情况相符。结论:该研究为栀子药材商品的综合质量评价提供了一种新方法。Objective： To evaluate the quality of Gardeniae Fructus based on grey incidence degree method. Method： Twenty samples of Gardeniae Fructus from different origins were collected to determine the contents of six main compositions. Then the quality evaluation models were set up by using grey incidence degree method. Result： The Gardeniae Fructus medicinal materials quality evaluation model was established, and an objective evaluation of the 20 samples from different origins was conducted, and the results showed that the relative correlation degree of all evaluation unit sequences was between 0. 309 7-0. 524 4. Seven batches of samples had a relative correlation degree above 0. 450, which had high quality evaluation. Among them, batches 1, 2, 7, 12 and 19 ranked top five in the quality, indicating that the samples produced in these areas had better quality. Meanwhile, the medicinal material texture was consistent with the current standards for the division of the product specification （maturity, fullness and color depth）, fully illustrating that grey incidence analysis results were consistent with the actual situation of medicinal materials. Conclusion： This study could provide a new method for comprehensive quality evaluation of Gardeniae Fructus medicinal materials.

关 键 词：栀子 质量评价 灰色关联分析法 

分 类 号：R284.1[医药卫生—中药学]