升红颗粒对小鼠化疗后血小板减少症的疗效研究  

Treatment effects of shenghong granules on thrombocytopenia after chemotherapy in mice

作　　者：董晓敏[1] 毛柳珺[1] 陈铂[1] 李江[1] 韦雨化 覃酒 

机构地区：[1]桂林医学院附属医院药学部,广西桂林541001

出　　处：《华夏医学》2017年第2期6-8,共3页Acta Medicinae Sinica

基　　金：广西壮族自治区卫生厅中医药科技专项课题资助(GZYZ1224)

摘　　要：目的:观察升红颗粒对小鼠化疗后血小板减少症的治疗作用。方法:构建小鼠化疗后血小板减少症模型,随机分为模型组、阿胶组和升红颗粒高、中、低剂量组,另设正常对照组,灌胃给药干预,分别于造模后第2天、第5天、第8天观察血小板计数水平。结果:升红颗粒各剂量组血小板计数均高于模型组,且存在剂量-效应关系,差异有统计学意义(P<0.01)。结论:升红颗粒可以促进血小板计数水平升高。Objective： To observe the treatment effects of shenghong granules on thrombocytopenia after chemotherapy in mice. Methods： The model of thrombocytopenia after chemotherapy were established in mice,which were randomized into the model group,the sss-hide gelatin group,shenghong granules high,medium and low dose groups. At the same time,normal control group was set with normal mice. Drugs were given to mice intragastrically,platelet counts were observed on the respective 2,5,8 days after model was established. Results： Platelet counts of every group of shenghong granules were higher than that of the model group,and there was correlation between dose and effect,which were of statistical differences（P〈0.01）. Conclusion： Shenghong granules can increase platelet counts.

关 键 词：升红颗粒 化疗 血小板减少症 

分 类 号：R558.2[医药卫生—血液循环系统疾病]