超声弹性成像与造影联合应用诊断甲状腺结节的临床价值  

Clinical value of contrast-enhanced ultrasonography in the differential diagnosis of thyroid nodules

作　　者：张桦[1] 

机构地区：[1]河南省安阳市肿瘤医院超声科,河南安阳455000

出　　处：《医学影像学杂志》2017年第6期1060-1062,1078,共4页Journal of Medical Imaging

摘　　要：目的探讨超声弹性成像与超声造影联合诊断与鉴别诊断良恶性甲状腺结节的价值。方法选取2014年11月~2016年11月120例甲状腺结节患者作为本次研究对象,均采用超声弹性成像、超声造影检查,并以手术病理结果为最终诊断标准。统计各组检查准确度、特异度、敏感度、阳性预测值及阴性预测值。结果超声弹性成像联合超声造影检查组(联合组)敏感度明显高于单一的超声造影组和超声弹性成像组,x^2=15.22,9.31,P=0.00;而超声造影组与超声弹性成像组间相比,x^2=0.63,P=0.38。联合组检查特异度明显高于超声造影组、超声弹性成像组,x^2=8.75,10.33,P=0.00;而超声弹性成像组、超声造影组比较,x^2=0.38,P=0.48。联合组检查准确度、阳性预测值、阴性预测值明显高于常规超声造影组、超声弹性成像组,x^2=12.72,24.36,16.11,P=0.00。结论临床应用超声弹性成像、超声造影联合诊断与鉴别诊断良恶性甲状腺结节均具有较高诊断价值,但单一的检查手段对鉴别甲状腺结节良恶性无明显差异,联合超声弹性成像与超声造影可提高甲状腺结节诊断敏感度,有利于甲状腺恶性肿瘤的早期发现、及时治疗。Objective To explore the role of ultrasound elastography and contrast-enhanced ultrasonography in the differential diagnosis of benign and malignant thyroid nodules. Methods 120 patients with thyroid nodules from November 2014 to December2016 were selected as the subjects. Ultrasonography,contrast-enhanced ultrasonography and ultrasonography were used to evaluate the histopathological results. The accuracy,specificity,sensitivity,positive predictive value and negative predictive value of each group were statistically analyzed. Results Ultrasonography combined with ultrasound contrast group（ combined group） was significantly higher than the sensitivity of ultrasound contrast group,ultrasound elasticity imaging group,x^2= 15. 22,9. 31,P =0. 00; and ultrasound contrast group and ultrasound elastic imaging group,x^2= 0. 63,P = 0. 38. The specificity of the combined group was significantly higher than that of the contrast-enhanced ultrasound group and ultrasound-enhanced ultrasound group,x^2= 8. 75,10. 33,P = 0. 00,while,the ultrasound-enhanced ultrasound group and the contrast-enhanced ultrasound group were x^2= 0. 38 and P = 0. 48. The accuracy,positive predictive value and negative predictive value of combined group were significantly higher than those of conventional ultrasound group and ultrasound elastic imaging group（ x^2= 12. 72,24. 36,16. 11,P = 0. 00）.Conclusion Clinical application of ultrasound elastography,contrast-enhanced ultrasonography,differential diagnosis of benign and malignant thyroid nodules have a high diagnostic value,but the use of a simple means of identification of benign and malignant thyroid nodules had no significant difference. Combined with ultrasound elastography and contrast enhanced ultrasound can in cases sensitivity of thyroid nodule diagnosis,which is conducive to early detection,diagnosis of early thyroid cancer,and the improvement of prognosis of patients with reference.

关 键 词：超声造影 超声弹性成像 甲状腺结节 良恶性 诊断 

分 类 号：R445.11[医药卫生—影像医学与核医学] R736.1[医药卫生—诊断学]