中药内服治疗单纯性肥胖的用药规律研究  

Analysis on Medication Rule in Herbal Prescriptions for Simple Obesity

作　　者：潘碧琦[1] 郑秋萍[1] 刘嘉芬[1] 夏燕琼[1] 

机构地区：[1]广东省妇幼保健院,广东广州510010

出　　处：《中医药导报》2017年第12期49-51,56,共4页Guiding Journal of Traditional Chinese Medicine and Pharmacy

基　　金：广东省中医药管理局科研项目(20121004)

摘　　要：目的:分析单纯性肥胖的中药内服处方的用药规律。方法:通过中国知网、重庆维普、万方、中国生物医学文献数据库搜集2013—2016年治疗单纯性肥胖的中药处方,采用TCMISS中医传承辅助平台软件提取分析处方中各药物的使用频次、四气五味归经、归类以及药物之间的关联规则等。结果:对130个中药处方进行分析,使用频率较高的中药有茯苓、白术、黄芪、山楂、半夏、泽泻、防己、大黄、甘草、决明子、天麻、橘红等。药物的四气分布主要为温、平、寒。药物的五味分布主要为甘、苦、辛。药物的归经分布主要为脾、胃、肺。处方中药物的归类分布主要为菊科、豆科、多孔菌科。半夏、白术、天麻、茯苓、橘红、甘草等均为临床治疗单纯性肥胖的常用中药。结论:中药治疗单纯性肥胖以健脾祛湿化痰为主要治法,常用处方为半夏白术天麻汤,关键药物组合是白术与茯苓,处方用药应以"祛湿化痰不伤脾,补泻兼施不恋邪"为原则。Objective： To analyze the medication rule in herbal prescriptions for simple obesity. Methods： Herbal prescriptions for simple obesity were searched from Chinese National Knowledge Infrastructure, VIP database, Wanfang database and Chinese Biomedical Database, from 2013 to 2016. We used Chinese medicine inheritance support system （TCMISS） to analyze the frequency, four natures, five flavors, meridian entry, plant classification of drugs, and the association rules between drugs. Results： Based on the analysis of 130 herbal prescriptions, herbs used with high frequency were Fuling （Poria cocos）, Baizhu （Bighead Atractylodes Rhizome）, Huangqi （Radix Astragali）, Shanzha （Hawthorn）, Banxia （Pinellia teruate）, Zexie （Rhizoma Alismatis）, Fangji （Stephania Tetrandra）, Dahuang （Rheum Officinale）, Gancao （Radix Liquiritiae）, Juemingzi （Semen Cassiae）, Tian- ma （Rhizoma Gastrodiae）, Juhong （Dried Tangerine）, et al. Four natures of drugs were mainly consisting of warmth, neutral and coldness. Five flavors of drugs were mainly consisting of sweet, bitter and pungent. Meridi- an entries were mainly consisting of spleen, stomach and lung. Plant classification of drugs was mainly consist- ing of Compositae, Leguminosae and Polyporaceae. Banxia （Pinellia ternate）, Baizhu （Bighead Atractylodes Rhi- zome）, Tianma （Rhizoma Gastrodiae）, Fuling （Poria cocos）, Juhong （Dried Tangerine） and Gancao （Radix Liquiri- tiae） were the most commonly used traditional Chinese Medicine for simple obesity. Conclusion： The main prin- ciples of treatment for simple obesity is tonifying spleen, dispelling wet and resolving phlegm. The most com- monly used traditional Chinese medicine prescription was BanXia BaiZhu TianMa Decoction （半夏白术天麻汤）. The key drug combination is Baizhu （Bighead Atractylodes Rhizome） and Fuling （Poria cocos）. We emphasize the medication principle that the medicine should dispel wet and resolve phlegm but not hurt the sple

关 键 词：单纯性肥胖 中药处方 组方规律 关联规则 聚类算法 

分 类 号：R259[医药卫生—中西医结合]