通脉定眩汤联合手法对颈椎病血液流变学及预后的改善研究  

Study on the improvement of hemorheology and prognosis of cervical spondylopathy by tongmai dingxuan decoction combined with manipulation

作　　者：张自强[1] 杨万期 曹顺金 ZHANG Zi-qiang YANG Wan-qi CAO Shun-jin(Department of Chinese Medicine, TianjinBaodi People＇s Hospital, Baodi Clinical Medicine of Tianjin Medical University, Tianjin 301800, China Tianjin Baodi traditional Chinese Medicine Hospital, Tianjin 301800, China)

机构地区：[1]天津市宝坻区人民医院,天津医科大学宝坻临床学院中医科,天津301800 [2]天津市宝坻区中医医院外科,天津301800

出　　处：《中国生化药物杂志》2017年第6期131-133,共3页Chinese Journal of Biochemical Pharmaceutics

摘　　要：目的 研究通脉定眩汤联合手法对颈椎病血液流变学及预后的改善情况.方法 选取天津市宝坻区人民医院中医科2014年11月-2015年11月收治的106例颈椎病患者,抽签随机分为观察组与对照组,每组53例,对照组给予手法治疗,观察组给予通脉定眩汤联合手法治疗,比较2组患者临床治疗有效率和治疗前后全血高切黏度、全血低切黏度、血浆黏度、全血还原黏度、红细胞压积、红细胞聚集指数、纤维蛋白原等血液流变学参数变化情况,对2组患者进行为期1年的随访观察,比较1年期间的复发率.结果 观察组患者的临床治疗总有效率为92.45%较对照组77.36%高,差异有统计学意义（P〈0.05）;观察组患者全血低切黏度（7.01±1.52）mPa＆#183;s、全血还原黏度（1.18±0.28）mPa＆#183;s、纤维蛋白原（3.91±0.94）g/L水平较对照组（7.88±1.65）mPa＆#183;s、（1.47±0.34）mPa＆#183;s、（4.51±0.98）g/L低,差异有统计学意义（P〈0.05）;观察组患者的复发率为13.21%较对照组30.19%低,差异有统计学意义（P〈0.05）.结论 通脉定眩汤联合手法治疗颈椎病疗效显著,患者全血黏度降低,血液循环功能得到改善,治疗后复发率低,值得临床上应用推广.Objective To study the improvement of hemorheology and prognosis of cervical spondylosis by Tongmai Dingxuan Decoction combined with Manipulation.MethodsA total of 106 patients with cervical spondylopathy in our hospital from November 2014 to November 2015 were randomly divided into observation group and control group,with 53 cases in each group.The control group were treated with manipulation,the observation group was treated with Tongmai Dingxuan Decoction combined with manipulation.The changes of hemorheology parameters such as high blood viscosity, whole blood low shear viscosity, plasma viscosity, whole blood reduction viscosity, hematocrit, erythrocyte aggregation index, fibrinogen were compared between the two groups before and after treatment.The two groups of patients were observed for a one-year follow-up, one year recurrence rate were compared.ResultsThe total effective rate was 92.45% in the observation group was significantly higher than that in the control group 77.36% （P〈0.05）.The whole blood low shear viscosity （7.01±1.52） mPa＆#183;s, the whole blood viscosity （1.18±0.28） mPa＆#183;s, fibrinogen （3.91±0.94） g/L were significantly lower than those in the control group （7.88±1.65） mPa＆#183;s, （1.47±0.34） mPa＆#183;s, （4.51±0.98） g/L （P〈0.05）.The recurrence rate in the observation group was 13.21%, which was significantly lower than that in the control group （30.19%） （P〈0.05）.ConclusionTongmai Dingxuan Tang combined with manipulation in the treatment with cervical spondylosis is significant, the whole blood viscosity is reduced, blood circulation function is improved, the recurrence rate after treatment is low, which is worthy of clinical application.

关 键 词：通脉定眩汤 手法 颈椎病 血液流变学 

分 类 号：R274[医药卫生—中医骨伤科学]