联合毛果芸香碱滴眼液治疗外伤引起房角后退继发性青光眼的临床疗效  

The clinical efficacy of combined pilocarpine eye drops in the treatment of traumatic angle recession glaucoma

作　　者：卢万宝 苏平 LU Wan-bao SU Ping(Department of Ophthalmology, Ningxia Hui Autonomous Region People＇s Hospitalm, Qingtongxia 751600, China)

机构地区：[1]宁夏回族自治区青铜峡市人民医院眼科

出　　处：《中国生化药物杂志》2017年第6期221-223,共3页Chinese Journal of Biochemical Pharmaceutics

摘　　要：目的 探讨联合毛果芸香碱滴眼液治疗外伤引起房角后退继发性青光眼的临床疗效.方法 完整收集78例外伤引起房角后退继发性青光眼患者的临床资料予以回顾性分析研究,资料收集时间为2015年12月-2016年12月.按照入院时间进行随机分组,对照组（38例）给予常规治疗,观察组（40例）给予常规疗法联合毛果芸香碱滴眼液.观察统计2组不同时间的眼压、瞳孔直径,并进行疗效判定和比较.结果 治疗后2组患者眼压均明显下降,与本组治疗前比较差异均有统计学意义,且治疗后不同时间组间比较观察组均显著低于对照组,经比较差异均有统计学意义（均P〈0.05）;治疗后7d 2组患者瞳孔直径均明显缩小,与本组治疗前比较差异均有统计学意义,且治疗后不同时间组间比较观察组均显著小于对照组,经比较差异均有统计学意义（均P〈0.05）;不同的治疗方案下对2组治疗有效率评估结果进行分析,观察组治愈的一共有21例,无效仅2例,总有效率为95.00%,与对照组存在组间差异有统计学意义（P〈0.05）.结论 常规疗法联合毛果芸香碱滴眼液对外伤引起房角后退继发性青光眼患者进行治疗效果确切,可显著降低眼压,缩小瞳孔,提高有效率.Objective To evaluate the clinical efficacy of combined pilocarpine eye drops in the treatment of traumatic angle recession glaucoma.MethodsThe clinical data of the patients were collected and analyzed retrospectively.The data collection time was December 2015 to December 2016.Were randomly divided into two groups according to the time of admission, the control group （38 cases） received routine treatment, the observation group （40 cases） treated with conventional therapy combined with pilocarpine eye drops.The IOP and pupil diameter of two groups were observed and compared.ResultsAfter treatment, two groups of patients with intraocular pressure were significantly decreased, compared with the group before treatment, there were statistically significant differences, and different time after the treatment were compared between the observation group were significantly lower than the control group, the difference was significant （P〈0.05）;after two 7d of treatment group were significantly reduced compared to the diameter of the pupil.Compared with the group before treatment, there were statistically significant differences, and different time after the treatment were compared between the observation group were significantly less than the control group, the difference was significant （P〈0.05）;efficiency evaluation results of two groups under different treatment, the observation group treated a total of 21 cases invalid, only 2 cases, the total effective rate was 95.00%, and there was no statistic difference between control group （P〈0.05）.ConclusionThe conventional therapy combined with pilocarpine eye drops on injury caused by angle recession glaucoma patients for treatment can significantly reduce intraocular pressure, miosis, improve efficiency.

关 键 词：外伤 房角后退 继发性青光眼 毛果芸香碱 

分 类 号：R755[医药卫生—皮肤病学与性病学]