胺碘酮联合美托洛尔在心律失常临床治疗中的应用研究  

Application of amiodarone combined with Mei TORO M in the treatment of arrhythmia

作　　者：赖娜[1] 饶红[1] 杨姣[2] 恩歌 LAI Na RAO Hong YANG Jiao EN Ge(Affiliated Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430000, China People＇s Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China Tianjin Ocean Oil General Hospital, Tianjin 300452, China)

机构地区：[1]华中科技大学同济医学院附属梨园医院,湖北武汉430000 [2]广西壮族自治区人民医院,广西南宁530021 [3]天津海洋石油总医院,天津300452

出　　处：《中国生化药物杂志》2017年第6期228-229,232,共3页Chinese Journal of Biochemical Pharmaceutics

摘　　要：目的 研究分析胺碘酮联合美托洛尔对于心律失常的临床治疗效果.方法 选取我院2015年8月到2016年9月收治的100例冠心病心律失常患者作为本次研究过程中的研究对象, 随机分对照组和实验组2组,每组患者各为50例.对照组患者的治疗方法为常规心律失常治疗,实验组患者在常规治疗的基础上进行胺碘酮联合美托洛尔治疗.比较分析实验组与对照组患者的临床治疗效果指标.结果 经过对应的治疗方式后,实验组50例患者中,18例患者的治疗效果为无效,12例患者为有效,20例患者为显效,总有效例数为32例,治疗有效率为64.0%.对照组50例患者中,29例患者为无效,8例患者为有效,13例患者为显效,总有效例数为21例,治疗有效率为42.0%.由此可得,实验组患者的治疗有效率显著高于对照组患者,具有统计学差异（P〈0.05）.实验组患者舒张压以及收缩压和心率等指标均显著优于对照组患者,差异具有统计学意义（P〈0.05）.实验组与对照组患者的不良反应发生概率比较差异无统计学意义.结论 胺碘酮联合美托洛尔对于心律失常治疗效果较好,应用较为广泛,能够在很大程度上提高治疗有效率,治疗安全性较高,具有临床进一步推广和应用的意义.Objective To study the clinical efficacy of amiodarone combined with metoprolol in the treatment of arrhythmia.Methods100 cases of patients with coronary heart disease arrhythmia treated in our hospital from August 2015 to September 2016 were selected as the research object in this study.They were randomly divided into the control group and the experimental group, each group had a total of 50 cases.Patients in the control group were treated with conventional arrhythmia treatment, and the experimental group was treated with amiodarone combined with metoprolol on the basis of conventional treatment.Comparative analysis of the experimental group and the control group of patients with clinical therapeutic effect index.ResultsAfter the corresponding treatment, the experimental group of 50 patients, the therapeutic effect of 18 cases were invalid, 12 cases were effective, 20 cases were markedly effective, the total effective number of cases to 32 cases, the effective rate was 64.0%.In the control group of 50 patients, 29 patients were invalid, and the effective rate was effective in all of the 8 patients.The effective rate of the treatment was effective in all of the 13 patients, with a total effective rate of 42.0%.Therefore, the effective rate of the experimental group was significantly higher than that of the control group, with statistical difference （P〈0.05）.The diastolic blood pressure, systolic blood pressure and heart rate in the experimental group were significantly better than those in the control group （P〈0.05）.There was no significant difference between the experimental group and the control group in the incidence of adverse reactions, which was not statistically significant.ConclusionAmiodarone Combined with metoprolol for treatment of arrhythmia is better, more widely used, can improve the treatment efficiency to a great extent, the treatment of high safety, with further clinical promotion and application.

关 键 词：胺碘酮 美托洛尔 心律失常 

分 类 号：R972[医药卫生—药品]