关节腔注射玻璃酸钠联合心理干预治疗膝关节骨性关节炎疗效观察  

Observation of the effect of intra-articular injection of sodium hyaluronate combined with psychological intervention in the treatment of knee osteoarthritis

作　　者：李云[1] 尹会[2] 阮文东[2] LI Yun YIN Hui RUAN Wen-dong(Pharmacy Department, General Hospital of Tianjin Medical University, Tianjin 300052, China Department of Orthopedics, General Hospital of Tianjin Medical University, Tianjin 300052, China)

机构地区：[1]天津医科大学总医院药剂科,天津300052 [2]天津医科大学总医院骨科,天津300052

出　　处：《中国生化药物杂志》2017年第6期339-341,共3页Chinese Journal of Biochemical Pharmaceutics

摘　　要：目的 探讨关节腔注射玻璃酸钠联合心理干预治疗膝关节骨性关节炎患者的临床效果.方法 选取2015年6月-2016年6月天津医科大学总医院诊治的90例膝关节骨性关节炎患者作为研究对象,根据治疗方式不同分为2组,每组45例.对照组患者采用常规方式治疗,观察组患者用常规方式＋关节腔注射玻璃酸钠治疗;比较2组患者各项实验数据.结果 观察组患者治疗后膝关节疼痛评分、关节积液量与关节活动度变化情况优于对照组;观察组患者治疗后膝关节功能评分变化情况优于对照组;观察组临床治疗效果（95.6%）优于对照组（75.6%）.组间比较差异均有统计学意义（P〈0.05）;2组患者接受治疗中均未出现严重不良反应,组间比较差异无统计学意义.结论 用常规方式＋关节腔注射玻璃酸钠治疗膝关节骨性关节炎患者临床效果佳,值得临床上广泛应用.Objective To investigate the clinical effect of intra-articular injection of sodium hyaluronate combined with psychological intervention in the treatment of knee osteoarthritis.MethodsA total of 90 patients with knee osteoarthritis treated in our hospital from June 2015 to June 2016 were selected as the research object, according to the different treatment methods, the patients were divided into two groups,with 45 cases in each group.The patients in the control group were treated with conventional treatment, while the observation group was treated with conventional therapy and intra-articular injection of sodium hyaluronate.The experimental data of the two groups were compared.ResultsAfter treatment, the changes of knee joint pain score, joint effusion and joint mobility in the observation group is better than those in the control group.The change of knee function score in the observation group was better than that in the control group.The clinical therapeutic effect of the observation group （95.6%） is better than that of the control group （75.6%）;There was significant difference between the two groups （P〈0.05）;There were no serious adverse reactions in the two groups of patients receiving treatment,and there was no significant difference between the two groups.ConclusionThe clinical effect of intra-articular injection of sodium hyaluronate combined with psychological intervention in the treatment of knee osteoarthritis is good, which is worthy of clinical application.

关 键 词：膝关节 骨性关节炎 关节腔 玻璃酸钠 

分 类 号：R684.3[医药卫生—骨科学]