正常前列腺^(18)F-FDG PET/CT显像的FDG摄取研究  

The FDG uptake of the normal prostate gland with ^(18)F-FDG PET/CT imaging

作　　者：陈雯[1] 张建飞[1] 刘秀芹[1] CHEN Wen ZHANG Jianfei LIU Xiuqin(Department of Nuclear Medicine, Beijing Hospital, Beijing 100730, China)

机构地区：[1]北京医院核医学科,北京100730

出　　处：《中国医药导报》2017年第16期102-105,共4页China Medical Herald

基　　金：北京医院博士启动基金(BJ-2015-110)

摘　　要：目的探讨正常前列腺^(18)F-FDG PET/CT显像中的放射性摄取范围及其影响因素。方法回顾性分析2014年11月~2016年1月于北京医院因非前列腺疾病而行^(18)F-FDG PET/CT全身显像的男性患者83例,年龄20~91岁,平均(60±18)岁。分析其PET/CT图像的影像学特征。采用感兴趣区(ROI)技术获得前列腺最大及平均FDG标准化摄取值(SUV)即SUVmax及SUVavg,并在最大横断层面测定前列腺直径。采用SPSS 17.0统计软件包对前列腺SUVmax、SUVavg与患者的年龄及前列腺大小行Pearson相关性分析。结果正常前列腺SUVmax平均值为2.3±0.4,SUVavg平均值为1.6±0.3,前列腺直径平均值为(4.4±0.7)cm。前列腺大小与年龄呈正相关关系(r=0.365,P<0.05),而前列腺SUV值(SUVmax及SUVavg)与年龄、前列腺大小无显著相关关系(P>0.05)。结论正常前列腺体积随着年龄增长而增加,但其在^(18)F-FDG PET/CT上的FDG摄取值并不受年龄及前列腺大小的影响。Objective To determine the FDG uptake of the normal prostate gland with ~SF-FDG PET/CT imaging and its influence factors. Methods The normal prostates in 83 men detected by ISF-FDG PET/CT imaging in Beijing Hos- pital from November 2014 to January 2016 were analyzed retrospectively, aged 20-91, average of （60_＋18） years. Their PET/CT imaging characteristics were analyzed. ROI technology was used for getting the SUVmax and SUVavg, and the diameters of prostate gland were detected in the maximum shear plane. Correlations among the SUV, prostate size and age were analyzed by Pearson correlation analysis with SPSS 17.0. Results The average of SUV maximum and mean was （2.3＋_0.4） and （1.6_＋0.3） respectively. The average of normal prostate gland size was （4.4_＋0.7） cm. There was posi- tive correlation between prostate size and age （r=0.365, P 〈 0.05）, but there was no statistically significant relationship between the SUV （SUVmax and SUVavg） and the size of normal prostate gland （P 〉 0.05）, the SUV （SUVmax and SU- Vavg） of the prostate gland was not significantly related with age also （P 〉 0.05）. Conclusion The prostate gland size get larger as age increased, but the age and the size are not influence the FDG uptake of the prostate gland with ISF- FDG PET/CT imaging.

关 键 词：前列腺 体层摄影术 发射型计算机 脱氧葡萄糖 

分 类 号：R445.3[医药卫生—影像医学与核医学]