瑞芬太尼复合丙泊酚靶控输注在妇科腹腔镜手术中的应用研究  

Research on application of target-controlled infusion of Remifentanil compounded with Propofol in gynecologic laparoscopic surgery

作　　者：李国强[1] 刘金龙[1] 李斌[1] 

机构地区：[1]赣南医学院第一附属医院麻醉科,江西赣州341000

出　　处：《中国当代医药》2017年第17期111-113,共3页China Modern Medicine

摘　　要：目的探讨瑞芬太尼复合丙泊酚靶控输注在妇科腹腔镜手术中的应用。方法选取2014年12月~2016年4月在我院择期行妇科腹腔镜手术的100例患者,随机分为观察组和对照组,各50例。观察组采用瑞芬太尼复合丙泊酚靶控输注麻醉,对照组采用芬太尼复合丙泊酚靶控输注麻醉,比较两组的术后恢复指标、血压和心率变化以及不良反应发生率。结果观察组的呼吸恢复时间、睁眼时间和拔管时间均明显短于对照组,差异有统计学意义(P<0.05)。观察组插管后1 min和气腹后3 min时的SBP、DBP、HR三项指标均明显低于对照组,差异有统计学意义(P<0.05)。观察组的不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论瑞芬太尼复合丙泊酚靶控输注可有效维持血流动力学稳定,促进患者尽早苏醒,且不良反应较少,麻醉效果理想,可以在妇科腹腔镜手术中广泛应用,具有较高的临床应用价值。Objective To investigate the application of target-controlled infusion（TCI） of Remifentanil compounded with Propofol in gynecologic laparoscopic surgery.Methods Altogether 100 patients who were scheduled to undergo gynecological laparoscopic surgery from December 2014 to April 2016 in our hospital were selected and randomly divided into the observation group and the control group,with 50 cases in each group.The observation group was treated with TCI anesthesia of Remifentanil compounded with Propofol,while,the control group was treated with TCI anesthesia of Fentanyl compounded with Propofol.The postoperative recovery index,blood pressure and heart rate changes and the incidence rate of adverse reactions were compared between the two groups.Results The respiratory recovery time,eye opening time and extubation time of the observation group were significantly shorter than those of the control group,with significant difference（P〈0.05）.The level of systolic blood pressure（SBP）,diastolic blood pressure（DBP） and heart rate（HR） at post-extubation 1 min and post-pneumoperitoneum 3 min of the observation group were significantly lower than those of the control group,with significant difference（P〈0.05）.The incidence rate of adverse reaction rate of the observation group was lower than that of the control group,with significant difference（P〈0.05）.Conclusion TCI of Remifentanil compounded with Propofol can effectively maintain hemodynamic stability and promote patients, early recovery with less adverse reactions and ideal anesthesia effect,which can be widely used in gynecological laparoscopic operation and is of great significance in clinical application.

关 键 词：瑞芬太尼 丙泊酚 芬太尼 妇科腹腔镜手术 

分 类 号：R614.24[医药卫生—麻醉学]