子宫肌瘤发病的相关因素和中医证型研究  

Related factors and TCM syndrome of uterine myoma

作　　者：王瑞婷[1] 须义贞[1] 梁阿娟 赵莉[1] WANG Ruiting XU Yizhen LIANG Ajuan ZHAO Li(Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China Shanghai Guanghua Hospital, Shanghai 200052, China)

机构地区：[1]上海中医药大学附属岳阳中西医结合医院,上海200437 [2]上海市光华中西医结合医院,上海200052

出　　处：《吉林中医药》2017年第6期571-574,共4页Jilin Journal of Chinese Medicine

基　　金：国家中医重点专科(中医妇科);国家中医药管理局"朱氏妇科流派传承工作室项目;上海市卫生局进一步加快中医药事业发展三年行动计划(海派中医流派传承研究基地)(ZY3-CCCX-1-1013);国家自然科学基金青年基金资助项目(30901919)

摘　　要：目的通过临床调查,从一般情况、月经、婚育史、生活方式、环境及心理因素、遗传因素、年龄等诸多因素中找出女性子宫肌瘤发病的危险因素,并对中医证型分布进行研究,找出子宫肌瘤多发的相关因素与中医证型分布的内在联系,为指导临床提供依据。方法运用统计学方法,通过300份问卷调查、性激素测定及B超检查,选用logistic回归分析、χ2检验等统计方法,分析子宫肌瘤发生的相关危险因素,找出子宫肌瘤多发的相关因素与中医证型分布的内在联系。结果 BMI体质量指数、子宫肌瘤家族遗传史、妊娠次数、流产次数、工作繁忙度与压力、情绪变化、常吃保健品、海鲜、吸烟是子宫肌瘤发病的危险因素。体育锻炼和规律作息是子宫肌瘤发病的保护因子。子宫肌瘤的中医证型分布特点以肾虚血瘀和气滞血瘀证型为主,BMI值、流产次数、情绪影响和病程长短与中医证型的分布相关性显著。中医证型分布随病程长短有所差异,初期短病程多分布在气滞血瘀证型,长病程多集中在肾虚血瘀证型。结论子宫肌瘤的发病与BMI体质量指数、妊娠次数、子宫肌瘤家族遗传史、工作繁忙度与压力等因素有较明显的相关性。子宫肌瘤的中医证型分布特点以肾虚血瘀和气滞血瘀证型为主,肾虚血瘀证型患者最多,痰湿瘀结证型患者最少。Objective Through clinical investigation, from the general situation, menstruation, obstevical history, life style, environmental and psychological factors, genetic factors, age, and many other factors to find women uterine fibroids disease risk factors, and to study related factors and TCM syndrome of uterine myoma, and to provide the basis for the clinical guidance.Methods Using statistical method, through the 300 questionnaires survey and the measurement of sex hormones and B ultrasonic examination, choose some statistical methods such as logistic regression analysis, chi-square test, analysis of the related risk factors of uterine fibroids and find out internal connecting link of related factors and TCM syndrome of uterine myoma.Results BMI, family heredity of uterine fibroids, pregnancy times, abortion times, job stress and pressure, emotion changes, often eating health products, seafood, smoking are risk factors for uterine flesh tumour disease. Physical exercise and regular work and rest are protection factors of uterine fibroids. The distribution characteristics of TCM syndrome types of uterine fibroids are kidney deficiency and blood stasis andqi stagnation and blood stasis, BMI, number of abortions, emotional impact and the length of the course were significantly correlated with the distribution of TCM syndromes. TCM syndrome type distribution along with the length of the course of the disease, early short duration distribution inqi stagnation and blood stasis type, long course of the disease more concentrated in the kidney deficiency and blood stasis syndrome.Conclusion The incidence of uterine fibroids and BMI, body mass index, number of pregnancy, the uterus myoma family genetic history, job stress and pressure and other factors have a significant correlation. The distribution characteristics of TCM syndrome types of uterine fibroids are kidney and blood stasis and qi and blood stasis syndrome type, kidney and blood stasis syndrome type is the most, and phlegm wet stasis syndrome type is the least.

关 键 词：子宫肌瘤 临床调查 发病因素 中医证型 

分 类 号：R271.1[医药卫生—中医妇科学]