MRI在Wernicke脑病的临床应用价值  

The clinical value of MRI in Wernicke Encephalopathy

作　　者：梁满球[1] 徐文[1] 

机构地区：[1]广东省东莞市人民医院放射科,广东东莞523059

出　　处：《现代医用影像学》2017年第2期203-206,共4页Modern Medical Imageology

摘　　要：目的:探讨Wernicke脑病(Wernicke's encephalophy,WE)的MRI表现特点,以提高诊断水平。方法:回顾性分析13例临床确诊WE的MRI影像学表现。结果:发生部位:9例病变累及双侧丘脑,5例病变累及乳头体,4例病变累及中脑导水管周围灰质,2例病变累及第三脑室周围灰质,累及第四脑室周围灰质、壳核、小脑齿状核、小脑上蚓、延髓、四叠体各1例。MRI表现:13例病变于T1WI为稍低信号,T2WI表现为高信号,FLAIR序列呈高信号;6例急性期病变DWI图像呈高信号,ADC图为低信号。1例增强扫描病例示乳头体呈结节状强化,1例增强扫描病例示中脑导水管边缘线状强化。结论:Wemicke脑病具有特征性的MRI表现,是诊断本病的重要影像学方法。Purpose：To explore MRI features of Wernicke Encephalopathy in order to improve accurate rate of diagnosis of this disease.Materials and Methods：MRI data of Wernicke Encephalopathy in 13 cases were retrospectively analyzed.Results：The lesion location：the lesion appeard at hibateral cerebral ganglion in 9 cases,at mammillary body in 5 cases,at the grey matter surrounding the aqueduct of mesencephalon in 4 cases,at the grey matter surrounding third ventricle of cerebrum in 2 cases,at the grey matter surrounding the fouth ventricle of cerebrum,dorsal caudate putamen,dentate body of cerebellum,cauda cerebelli,bulbus medullae and quadrigeminal bodies in each 1 case.The lesion of all cases appeard as hypointensity on T1WI,hyperintensity on T2WI and FLAIR.In 6 acute cases,the lesion appeard as hyperintensity on DWI.Mammillary body showed nodular enhancement in 1 case after administration of contrast medium.The edge of aqueduct of mesencephalon showed enhancement in 1 case after administration of contrast medium.Conclusion：Wernicke Encephalopathy has characteristic MRI findings.Typical symmetric damage of brain paraventricular region and mammillary bodies may permit a specific diagnosis of this disease.

关 键 词：脑 韦尼克脑病 磁共振成像 

分 类 号：R445.2[医药卫生—影像医学与核医学] R742[医药卫生—诊断学]