补气活血软肝煎对慢性乙型肝炎肝纤维化的临床疗效观察  

Clinical observation on the effect of Buqi Huoxue Ruangan decoction on chronic hepatitis B fibrosis

作　　者：蒋南飞[1] 欧阳兵[1] 贺柯庆[1] 

机构地区：[1]南昌市第九医院肝病科,江西南昌330002

出　　处：《中国现代医生》2017年第17期128-130,134,共4页China Modern Doctor

基　　金：江西省南昌市指导性科技计划项目(洪科发计字【2016】96号-71)

摘　　要：目的观察补气活血软肝煎在临床上对慢性乙型肝炎肝纤维化的治疗效果。方法采用对照试验的方法。对60例慢性乙型肝炎肝纤维化患者进行随机分组。其中,对照组(30例)口服恩替卡韦分散片予以治疗,治疗组(30例)则采用口服恩替卡韦分散片联合补气活血软肝煎进行治疗。6个月为1个疗程,观察1个疗程,观察两组的肝纤维化、肝功能、症状改善相关指标在治疗前后的变化。结果治疗组治疗后临床症状的改善效果优于对照组(P<0.05),肝纤维化指标、肝功能的治疗效果改善程度也优于对照组(P<0.05)。结论补气活血软肝煎能够改善慢性乙型病毒性肝炎肝纤维化的症状、改善肝功能和改善肝纤维化,能够有效地降低患者的慢性乙型病毒性肝炎肝纤维化的进程。Objective To observe the therapeutic effect of Buqi Huoxue Ruangan decoction on the treatment of chronic hepatitis B fibrosis in clinical. Methods Control test method was used. 60 patients with chronic hepatitis B fibrosis were randomly grouped. Among them, the control group （n=30） was treated with entecavir dispersible tablets. The treat merit group （n=30） was treated with oral entecavir dispersible tablets combined with Buqi Huoxue Ruangan decoction. 6 months was a course of treatment, and a course of treatment was observed. The liver fibrosis, liver function and symptomatic improvement related indexes of the treatment group and the control group were observed before and after treatment. Results The effect of improvement in clinical symptoms in the treatment group was better than that in the control group after treatment （P〈O.05）. The improvement degree of treatment effect of liver fibrosis indexes and liver function was better than that of the control group （P〈0.05）. Conclusion Buqi Huoxue Ruangan decoction can improve the symptoms of chronic hepatitis B fibrosis, liver function and liver fibrosis, and can effectively reduce the process of liver fibrosis in patients with chronic hepatitis B fibrosis.

关 键 词：慢性乙型肝炎 肝纤维化 补气活血软肝煎 恩替卡韦分散片 

分 类 号：R259[医药卫生—中西医结合]