不同炮制方法炮制藏药“君西”对大鼠胃溃疡的影响  

The Influence of Tibetan Medicine JunXi Prepared with Different Processing Methods on the Rats Suffering Gastric Ulcer

作　　者：王树林[1] 陈湘宏[1] 张发斌[1] 童丽[1] 康文娟[1] 翁裕馨[1] 

机构地区：[1]青海大学医学院,青海西宁810001

出　　处：《西部中医药》2017年第5期14-17,共4页Western Journal of Traditional Chinese Medicine

基　　金：青海大学科研基金项目(编号2012-QHT-4)

摘　　要：目的:探讨不同方法炮制藏药"君西"对大鼠胃溃疡的影响。方法:将建立的乙酸性胃溃疡模型大鼠(SD)88只随机分为11组:模型组、阳性组(甲氰咪胍)、传统炮制6组和现代炮制3组,连续早晚灌胃给药10天后处死,观察大鼠胃溃疡指数变化情况。结果:阳性组溃疡指数低于模型组,差异有统计学意义(P<0.01);不同炮制方法组溃疡指数均低于模型组,其中传统热制、传统滋补制、传统"灰"制、现代奶制组与模型组比较差异有统计学意义(P<0.01)。结论:不同方法炮制的藏药"君西"对大鼠乙酸型胃溃疡具有一定的治疗作用,其中传统热制、传统滋补制、传统"灰"制、现代奶制效果更优。Objective： To discuss the influence of Tibetan medicine JunXi prepared with different processing methods on the rats with gastric ulcer. Methods： All 88 rat models with acetic acid-induced gastric ulcer were ran- domized into 11 groups： the model group, positive group （tagamet）, six groups of traditional processing methods and three groups of modem processing method, the changes of gastric ulcer indexes of the rats were observed when the rats were sacrificed after they were lavaged for ten days consecutively in the morning and evening. Results： The pos- itive group was lower than the model group in ulcer index, and the difference showed statistical meaning （P〈0.01）; the groups of different processing methods were lower than the model group in ulcer index, and the difference had statistical meaning when traditional hot processing, traditional nourishing processing, traditional ash processing, modem milk processing were compared with the model group （P〈0.01）. Conclusion： Tibetan medicine JunXi pre- pared with different processing methods possesses certain therapeutic effects for the rats suffering acetic acid-in- duced gastric ulcer, and the effects of JunXi prepared with traditional hot processing, traditional nourishing process- ing, traditional ash processing, modem milk processing are more superior.

关 键 词：胃溃疡 君西 藏药炮制 

分 类 号：R285.5[医药卫生—中药学]