DWI多指数模态评价急性胰腺炎的诊断价值研究  

Diagnostic Value of Multi-b Value DWI Exponential Model for Acute Pancreatitis

作　　者：石林[1] 黄小华[1] 胡海[1] 邓巧[1] 刘翠兰[1] 潘珂[1] 

机构地区：[1]四川省医学影像学重点实验室川北医学院附属医院放射科

出　　处：《中国医学计算机成像杂志》2017年第3期222-227,共6页Chinese Computed Medical Imaging

基　　金：四川省教育厅基金No.16ZA0228~~

摘　　要：目的:比较单指数模型和基于体素内不相干运动(IVIM)DWI理论的双指数模型对急性胰腺炎(AP)的诊断价值。方法:按标准纳入52例AP患者(观察组)及31例健康志愿者(对照组),行上腹部常规MRI和0~1500s/mm^2多b值DWI成像,分别测量DWI单、双指数模型参数Standard ADC、slow ADC mono、fast ADC mono、Ff ADC mono、slow ADC Bi、fast ADC Bi、Ff ADC Bi值,比较其对AP的诊断效能。结果:独立样本t检验显示standard ADC、Ff ADC mono、Ff ADC Bi值差异有统计学意义,slow ADC mono、fast ADC mono、slow ADC Bi、fast ADC Bi值差异无统计学意义。ROC曲线显示standard ADC、Ff ADC mono、Ff ADC Bi有诊断效能(曲线下面积分别为0.670mm^2,0.777mm^2,0.643mm^2,P<0.05),Ff ADC mono与Ff ADC Bi的诊断效能差异有统计学意义,Ff ADC mono、Ff ADC Bi与standard ADC的诊断效能差异无统计学意义。结论:DWI单指数模型参数standard ADC及双指数模型参数Ff ADC mono、Ff ADC Bi对AP有较好的诊断价值,双指数模型参数Ff ADC mono较Ff ADC Bi对AP的诊断效能高。Purpose： To compare the diagnostic value of monoexponential and biexponential model of multi-b value DWI based on intravoxel incoherent motion theory for acute pancreatitis. Methods： A total of 52 patients with acute pancreatitis （AP） and 31 healthy volunteers were recruited. All subjects had performed conventional abdominal MRI and multi-b value DWI scans. The b values of 0-1500 s/mm^2 were selected to acquire the multi-b value DWI. The standard ADC, slow ADC mono, fast ADC mono, FfADC mono, slow ADC Bi, fast ADC Bi, FfADC Bi derived form monoexponential and biexponential model were measured, and the diagnostic value of them were compared for AP. Results： There were significant differences of monoexponential model parameters standard ADC, and biexponential model parameters Ff ADC mono, Ff ADC Bi between AP group and normal pancreatitis group, but the difference of slow ADC mono, fast ADC mono, slow ADC Bi, fast ADC Bi were with no statistical significant. ROC curves showed that standard ADC, FfADC mono, FfADC Bi had higher diagnostic value for AP （area under the ROC curve： 0.670mm^2, 0.777mm^2, 0.643mm^2, respectively, all P 〈 0.05）, there were significant differences between FfADC mono and Ff ADC Bi, there was no statistical significant differences between FfADC mono and standard ADC, as well as FfADC Bi and standard ADC. Conclusion： Monoexponential model parameters standard ADC, and biexponential model parameters Ff ADC mono, Ff ADC Bi demonstrated some diagnostic value for AP. Ff ADC mono was with higher diagnostic value than FfADC Bi.

关 键 词：急性胰腺炎 弥散加权成像 体素内不相干运动 

分 类 号：R445.2[医药卫生—影像医学与核医学]