成人腰椎不同部位表观弥散系数值的差异及与年龄的相关性  

MR diffusion weighted imaging study of lumbar spine in healthy adults

作　　者：赵云超[1] 程静[1] 李杰[1] 傅晗[1] 

机构地区：[1]昆明市中医医院,云南昆明650500

出　　处：《中国骨质疏松杂志》2017年第6期707-710,共4页Chinese Journal of Osteoporosis

摘　　要：目的通过磁共振扩散加权影像技术来研究正常健康人群的腰椎各部分的表观弥散系数之间的差异以及与年龄的相关性,为提高成人腰椎病变检查的准确性及可靠性。方法选取2015年07月至2016年08月期间来我院进行正常体检的人员,经筛选最终选择60例,其中男性为28例,女性为32例,平均年龄为(53.26±18.13)岁,分为中年、老年、青年三个年龄段组,进行腰椎正中矢状切面T2弛豫时间图像扫描,用以量化并分析腰椎内水分子的含量,同时进行腰椎正中矢状切面扩散加权影像扫描,用以分析腰椎内水分子的扩散程度,将获得的数据进行统计分析,分析不同年龄段组之间的腰椎各部分ADC值的差异。结果正常健康成人的腰椎不同部位的ADC值存在显著性差异(P<0.05),椎弓根的ADC值大于椎体;腰椎各部位的ADC值随年龄段的变化呈现显著性差异(P<0.05),青年组的ADC值大于中年组和老年组,老年组的ADC值最小。结论在以后研究腰椎病变时,一定要对照同样年龄段的正常健康人群来判定,这样才能提高诊断的效率和准确度。Objective With the aim of improving the accuracy and reliability of lumbar vertebral lesions examination,MRI diffusion weighted image technique was used to study the difference in apparent diffusion coefficients（ADC） between different parts of lumbar vertebrae in normal healthy subjects. Their correlation with age was also evaluated. Methods Sixty normal healthy adults（28 males and 32 females） were selected from people attending physical examination at our hospital from July 2015 to August2016,and were grouped according to age into young,middle-age and older age groups. Lumbar spine median sagittal T1-T2 relaxation time image scans were performed to quantify and analyze the water content of lumbar vertebrae,and the lumbar median sagittal plane diffusion weighted images were obtained to analyze the diffusion of water molecules in lumbar vertebrae. Data were obtained for statistical analysis,and the differences in ADC values of the various parts of the lumbar vertebrae in different age groups were analyzed. Results ADC values of different parts of lumbar vertebrae were significantly different（P〈0. 05）. ADC value of the pedicle was higher than that of the vertebral body. ADC values of different parts of lumbar vertebra showed significant difference between age groups（P〈0. 05）. The ADC value of the young adult group was higher than that of the middle-aged group and the older age group,and the ADC value of the older age group was the lowest. Conclusions Our study suggests that in the future,we should determine lumbar lesions according to data of normal healthy people of the same age group,in order to improve the efficiency and accuracy of diagnosis.

关 键 词：磁共振扩散加权影像 表观扩散系数 腰椎 椎体 椎弓根 

分 类 号：R681.5[医药卫生—骨科学]