2型糖尿病患者FRAX评分及骨密度与BMI的相关性分析  

Correlation among FRAX score,bone mineral density,and body mass index in patients with type 2 diabetes

作　　者：俞海燕[1] 郭晓珍[1] 黄文龙[1] 高远[1] 方铭[1] 胥娟[1] 吴心池[1] 陈华[1] 张晓兰[1] 

机构地区：[1]东南大学医学院附属江阴医院内分泌科,江苏无锡214400

出　　处：《中国骨质疏松杂志》2017年第6期761-763,767,共4页Chinese Journal of Osteoporosis

基　　金：江阴市卫计委科研项目面上项目(M201504)

摘　　要：目的探讨2型糖尿病患者骨折风险预测工具FRAX计算出的骨折风险及骨密度与BMI之间的关系。方法选取278例糖尿病人群,开展相关问卷调查,收集相关临床指标,并检测骨密度,计算FRAX评分。研究2型糖尿病患者FRAX评分及骨密度与BMI的关系。结果 2型糖尿病患者的L1-4、股骨颈的骨密度随着BMI的升高,呈逐渐升高的趋势(P<0.05),10年主要骨质疏松性骨折发生概率(PMOF)和10年髋部骨折发生概率(PHF)在分组后无明显差异。结论 2型糖尿病患者骨密度与BMI有相关性,而FRAX评分与BMI无相关性。Objective To explore the correlation among FRAX score,bone mineral density,and body mass index in patients with type 2 diabetes. Methods A standardized questionnaire was sent to a total of 278 subjects with type 2 diabetes. The clinical information was collected. Bone mineral density was detected and FRAX score was calculated. The relationship between clinical risk factors and complication of diabetes and FRAX score was assessed. Results The bone mineral density of the lumbar spine（L1-4）and the femur neck in DM group increased with the increase of BMI（P〈0. 05）. There is no obvious difference in the 10-year probability of hip fracture（PHF） and the 10-year probability of major osteoporotic fractures（PMOF） after grouping. Conclusion There is correlation between bone mineral density and BMI,but no correlation between FRAX score BMI in patients with type 2diabetes.

关 键 词：FRAX 骨密度 BMI 糖尿病 

分 类 号：R589[医药卫生—内分泌]