卡前列素氨丁三醇联合卡贝缩宫素在产后出血患者中的应用效果观察  

The Effect of Carboprost Combined with Carbetocin in Postpartum Hemorrhage

作　　者：罗健敏[1] 郭跃文[1] 廖桂霞[1] 

机构地区：[1]广东省佛山市顺德区第一人民医院,广东顺德528300

出　　处：《内蒙古医学杂志》2017年第2期154-156,共3页Inner Mongolia Medical Journal

摘　　要：目的观察卡前列素氨丁三醇联合卡贝缩宫素在产后出血患者中的应用效果。方法选取本院2015年8月至2016年8月收治的产后出血患者52例,随机分为2组,观察组26例患者采用卡前列素氨丁三醇联合卡贝缩宫素进行治疗,对照组26例患者单独采用卡贝缩宫素进行治疗,收集2组患者产后2h、产后24h的出血量及不良反应发生率数据并进行对比分析,得出结论。结果观察组患者的总有效率为96.15%,对照组患者的总有效率为80.77%,观察组显著高于对照组,差异具有统计学意义(P<0.05);治疗前,观察组患者与对照组患者的出血量无显著差异,不具有统计学意义(P>0.05);治疗后,观察组患者产后2h、产后24h的出血量均显著低于对照组,差异具有统计学意义(P<0.05);观察组患者的不良反应发生率为19.23%,对照组患者的不良发应发生率为61.54%,观察组显著低于对照组,差异具有统计学意义(P<0.05)。结论卡前列素氨丁三醇联合卡贝缩宫素治疗产后出血患者,可以显著降低出血量和不良反应发生率,临床应用效果显著,是一种值得广泛推广使用的治疗方法。Objective To observe the effect of carboprost combined with carbetocin in postpartum hemor- rhage. Methods Fifty - two patients with postpartum hemorrhage admitted in our hospital from August 2015 to August 2016 were randomly divided into two groups. In the observation group, 26 patients were treated with carboprost combined with carbetocin, Control group, 26 patients were treated with carbetocin alone, two groups of patients 2 hours postpartum, 24 hours postpartum hemorrhage and adverse reaction rate data and comparative analysis, conclusions. Results The total effective rate was 96.15 % in the observation group and 80.77 % in the control group, the difference was statistically significant（P 〈 0.05）. In the observation group, There was no significant difference between the two groups（P 〉 0.05）. The amount of blood loss in the observation group was significantly lower than that in the control group at 2 hours postpartum and 24 hours postpartum（P 〈 0.05）, the difference was statistically significant（P 〈 0.05）. The adverse reaction rate was 19.23 % in the observation group and 61.54% in the control group, which was significantly lower than that in the control group（P 〈 0.05）. Conclusion The combination of carboprost and carbetocin in the treatment of postpartum hemorrhage can significantly reduce the amount of bleeding and the incidence of adverse reactions. The clinical effect is re- markable. It is a widely used treatment method.

关 键 词：卡前列素氨丁三醇 卡贝缩宫素 产后出血 

分 类 号：R714.461[医药卫生—妇产科学]