CRRT联合灌流在脓毒症休克患者中的疗效观察及安全性研究  

Observation of CRRT+Perfusion in Patients with Septic Shock and Its Safety

作　　者：李彦嫦[1] 

机构地区：[1]广西科技大学第一附属医院,广西柳州545002

出　　处：《内蒙古医学杂志》2017年第2期156-158,共3页Inner Mongolia Medical Journal

摘　　要：目的探究CRRT(连续性肾脏替代治疗)+HA330血液灌流治疗在脓毒症休克患者临床应用中的价值。方法选取近期我院收治的脓毒症患者30例,随机均分为单独CRRT治疗对照组和CRRT联合HA330血液灌流治疗观察组,对比分析两组患者的APACHE II评分情况(急性生理与慢性健康评分)和患者MODS(多器官功能障碍综合征)、28d死亡率情况。结果观察组疗效比对照组疗效更加显著。观察组患者的APACHE II评分情况显著优于对照组,该组MODS和28d死亡率也显著低于对照组,P<0.05。结论对脓毒症患者进行CRRT+HA330血液灌流治疗可增加治疗有效性和安全性,提高患者存活率。Objective To explore the value of CRRT （continuous renal replacement therapy） ＋ HA330 hemoperfusion in the clinical application of septic shock. Methods Thirty patients with sepsis were randomly di- vided into CRRT group and CRRT group combined with HA330 hemoperfusion group. The APACHE II score （acute physiology and chronic health condition） of the two groups were compared and analyzed. ） And MODS （multiple organ dysfunction syndrome）, 28d mortality rate. Results The curative effect of observation group was more significant than that of control group. The APACHE II score of the observation group was significant- ly better than the control group, the MODS and 28d mortality rate in the group was also significantly lower than the control group, P 〈 0.05. Concision Hemoperfusion of CRRT ＋ HA330 in sepsis patients can increase the efficacy and safety of treatment and improve the survival rate of patients.

关 键 词：脓毒症休克 CRRT 血液灌流 

分 类 号：R541.64[医药卫生—心血管疾病]