经颅高频超声在高危新生儿室管膜下区病变诊断中的应用  

Application of transcranial high-frequency ultrasound in diagnosis of high risk neonatal subependymal lesion

作　　者：吴一彬 张勇强 方耿周 

机构地区：[1]广东省深圳市光明新区人民医院超声科,518106

出　　处：《中国实用医药》2017年第17期41-43,共3页China Practical Medicine

摘　　要：目的探讨经颅高频超声在高危新生儿室管膜下区病变诊断中的价值。方法对730例高危新生儿进行经颅脑高频超声检查,对图像进行分析。结果 730例新生儿中,61例室管膜下病变,18例单纯性室管膜下囊肿(SEC),43例室管膜下出血(SEH)。441例早产儿(<37周)中SEH患儿33例(33/441,7.48%);289例足月儿(≥37周)中SEH患儿10例(10/289,3.46%),两者SEH发生率比较差异有统计学意义(χ~2=5.097,P<0.05)。403例低体重儿(<2500 g)中SEH患儿35例(35/403,8.68%);327例正常体重儿(≥2500 g)中SEH患儿8例(8/327,2.45%),两者SEH发生率比较差异有统计学意义(χ~2=12.67,P<0.01)。结论胎龄越小、出生体重越低,室管膜下出血发生率越高;经颅高频超声可以针对性的观察高危新生儿室管膜下病变变化情况,有利于动态随访观察颅脑疾病的变化,指导临床治疗。Objective To investigate value by transcranial high-frequency ultrasound in diagnosis of high risk neonatal subependymal lesion. Methods A total of 730 high risk newborn received transcranial high- frequency ultrasound for examination, and their images were taken into analysis. Results Among 730 newborn, there were 61 cases with subependymal lesion, 18 cases with simple subependymal cyst （SEC） and 43 cases with subependymal hemorrhage （SEH）. There were 33 cases with SEH （33/441, 7.48%） among 441 premature infants （〈 37 weeks） and 10 cases with SEH （10/289, 3.46%） among 289 term infants （≥37 weeks）. Their difference of incidence of SEH had statistical significance （X^2=5.097, P〈0.05）. There were 35 cases with SEH （35/403, 8.68%） among 403 infants of low-birth weight （〈2500 g） and 8 cases with SEH （8/327, 2.45%） among 327 infants with normal birth weight （≥2500 g）. Their difference of incidence of SEH had statistical significance （X^2=12.67, P〈O.01）. Conclusion Younger gestational age and lower birth weight will lead to higher incidence of subependymal hemorrhage. Transcranial high-frequency ultrasound can provide targeted observation on subependymal lesion changes in high risk newborn. This method is helpful for dynamic follow-up and observation for changes in craniocerebral disease, and it can guide clinical treatment.

关 键 词：新生儿 高频超声 室管膜下病变 

分 类 号：R445.1[医药卫生—影像医学与核医学] R742[医药卫生—诊断学]