有创与无创序贯性机械通气治疗慢性阻塞性肺疾病致严重呼吸衰竭疗效分析  

Analysis of curative effect by invasive and non-invasive sequential mechanical ventilation in the treatment of severe respiratory failure caused by chronic obstructive pulmonary disease

作　　者：尚愚[1] 李雪莉[1] 

机构地区：[1]黑龙江哈尔滨市第一医院呼吸内二科,150010

出　　处：《中国实用医药》2017年第17期64-66,共3页China Practical Medicine

摘　　要：目的分析有创与无创序贯性机械通气治疗慢性阻塞性肺疾病致严重呼吸衰竭的临床效果。方法 64例慢性阻塞性肺疾病致严重呼吸衰竭患者,随机分为对照组和实验组,各32例。对照组实施经口气管插管接呼吸机进行辅助通气治疗,实验组患者采用有创与无创正压通气序贯治疗;对比分析两组患者临床疗效和临床治疗情况。结果实验组治疗有效率为93.75%;对照组治疗总有效率为71.88%;实验组治疗总有效率显著高于对照组,差异具有统计学意义(P<0.05)。实验组患者有创通气时间为(3.12±0.88)h、机械通气时间为(11.21±3.08)h,住院时间为(16.23±5.03)d,均显著的短于对照组的(7.22±1.27)h、(23.68±4.86)h、(28.21±5.87)d,差异具有统计学意义(P<0.05)。结论在慢性阻塞性肺疾病致严重呼吸衰竭患者的临床治疗中,有创与无创序贯性机械通气治疗可以有效的提高临床治疗效果,缩短患者的有创通气时间、机械通气时间和住院时间,在临床中具有推广和应用价值。Objective To analyze clinical effect by invasive and non-invasive sequential mechanical ventilation in the treatment of severe respiratory failure caused by chronic obstructive pulmonary disease. Methods A total of 64 patients with severe respiratory failure caused by chronic obstructive pulmonary disease were randomly divided into control group and experimental group, with 32 cases in each group. The control group received breathing machine through oral trachea cannula for assisted ventilation treatment, and the experimental group received invasive and non-invasive sequential mechanical ventilation for treatment. Comparative analysis was made on clinical effects and clinical treatment situation between the two groups. Results The experimental group had total effective rate in treatment as 93.75%, and the control group had total effective rate in treatment as 71.88%. The experimental group had obviously higher total effective rate in treatment than the control group, and the difference had statistical significance （P〈0.05）. The experimental group had invasive ventilation time as （3.12±0.88） h, mechanical ventilation time as （11.21 ± 3.08） h and hospital stay time as （16.23 ±5.03） d, which were all obviously shorter than （7.22 ± 1.27） h, （23.68 ± 4.86） h and （28.21 ± 5.87） d in the control group, and their difference had statistical significance （P〈O.05）. Conclusion In clinical treatment of patients with severe respiratory failure caused by chronic obstructive pulmonary disease, invasive and non-invasive sequential mechanical ventilation can effectively improve clinical effect, and shorten invasive ventilation time, mechanical ventilation time and hospital stay time in patients. This method contains value for clinical promotion and application.

关 键 词：慢性阻塞性肺疾病 有创与无创序贯性机械通气 呼吸衰竭 临床疗效 

分 类 号：R563.8[医药卫生—呼吸系统] R563.9[医药卫生—内科学]