疏血通联合低分子肝素钙抗凝在特重度烧伤救治中的疗效观察  

Effect of ShuXieTong(SXT)combined low molecular weight heparin calcium (LMWHC) anticoagulant therapy in extensive severe burn patients

作　　者：傅勇[1] 王宁宁[1] 李家光[1] 张志磊[1] 

机构地区：[1]滨州医学院附属医院烧伤整形外科,滨州256603

出　　处：《滨州医学院学报》2017年第3期189-191,共3页Journal of Binzhou Medical University

摘　　要：目的探讨疏血通联合低分子肝素钙抗凝在特重度烧伤治疗中的临床疗效。方法收集我院2014年1月至2016年10月收治的57例特重度烧伤患者的临床资料,根据病人不同治疗方案选入观察组与对照组,其中对照组采取常规治疗,观察组在常规治疗基础上加用疏血通联合低分子肝素钙抗凝治疗,比较两组患者治疗前后血小板数量、D-二聚体、凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)各项指标变化以及深静脉血栓发生情况。结果观察组与对照组比较治疗后各项指标均显著改善(P<0.05);观察组未发生静脉血栓,而对照组发生下肢深静脉血栓3例、肺栓塞1例。结论疏血通联合低分子肝素钙抗凝在特重度烧伤救治中可显著改善患者的凝血异常,有效预防静脉血栓栓塞的发生,值得临床推广应用。Objective To explore the effect of ShuXieTong（SXT） combined with low molecular weight heparin calcium （LM- WHC） therapy in severe burn patients. Methods The clinical data of 57 patients with severe burn in our institute （from Januar- y 2014 to October 2016 ）was retrospectively reviewed, and the 57 patients were assigned as SXT＋ LMWHC treatment group or control group randomly. The following platelet count（ PC）, D-dimer（D-D） , prothrombin time（ PT）, activated partial thrombo- plastin time（APTT）, deep vein thrombosis （DVT） were determined before and after the treatment. Results PC, D-D, PT, APTT were significantly lower in SXT＋LMWHC treatment group compared with that in control group after treatment （P〈 0.05） ;DVT was not detected in any of the patients in SXT＋LMWHC treatment group,while 3 case of DVT and 1 case of pul- monary embolism occurred in the control group. Conclusion SXT combined with LMWHC could ameliorate hypercoagulability following severe burns and prevent the occurrence of DVT effectively.

关 键 词：疏血通 低分子肝素钙 抗凝 特重度烧伤 

分 类 号：R644[医药卫生—外科学]