栓塞治疗颅内破裂动脉瘤术中再破裂的危险因素分析  

The risk factors for rerupture of ruptured intracranial aneurysm during intravascular embolization

作　　者：程旭峰[1] 傅先明[1] 钱若兵[1] 顾大群[1] 余舰[1] 牛朝诗[1] 汪业汉[1] 

机构地区：[1]安徽医科大学附属省立医院,合肥230001

出　　处：《安徽医学》2017年第6期679-683,共5页Anhui Medical Journal

基　　金：安徽省科技攻关计划项目(项目编号:1301042201)

摘　　要：目的探讨血管内治疗颅内破裂动脉瘤并发术中再破裂的危险因素。方法回顾性分析2010年1月至2015年12月安徽医科大学附属省立医院收治的678例经血管内栓塞治疗的颅内破裂动脉瘤患者的临床资料,通过单因素结合多因素分析探讨术中再破裂的相关危险因素。结果引起术中再破裂事件的危险因素有血管痉挛、动脉粥样硬化及动脉瘤大小(P<0.05),而性别、年龄、高血压病史、糖尿病病史、Hunt-Hess分级、瘤颈特征、治疗方案及治疗时间与术中再破裂无明显关系(P>0.05)。结论血管痉挛、动脉粥样硬化及微小动脉瘤是血管内治疗颅内破裂动脉瘤并发术中再破裂的危险因素,临床需谨慎选择手术方案,充分做好术中再破裂的预防。Objective To study the risk factors of intraprocedural re-rupture of ruptured intracranial aneurysms.Methods A total of 678 patients with ruptured intracranial aneurysm that received intravascular embolization were included in this study, including 20 cases that suffered rerupture of intracranial aneurysm during the surgery.The risk factors for intraoperativererupture were analyzed by univariate and multivariate analyses.Results Vasospasm, atherosclerosis and aneurysm size were the risk factors for intraoperativererupture （P〈0.05）;however, sex, age, history of hypertension, history of diabetes mellitus, Hunt-Hess grade, characteristics of the aneurysmal neck, surgical procedure and surgical time were not significantly correlated with incidences of rerupture of intracranial aneurysm.Conclusion Vasospasm, atherosclerosis, and micro-aneurysm are the risk factors for rerupture of intracranial aneurysm during intravascular embolization.

关 键 词：颅内动瘤 栓塞 并发症 

分 类 号：R651.12[医药卫生—外科学]