探讨支气管哮喘急性发作患者诱导痰嗜酸性粒细胞比例变化及肺功能的关系  

Investigation on the Relationship between Sputum Eosinophil Ratio and Pulmonary Function in Patients with Acute Exacerbation of Bronchial Asthma

作　　者：张志海[1] 陈嘉馨[1] 谭慧锋 李映梅[1] 

机构地区：[1]佛山市南海区第二人民医院,佛山528251

出　　处：《数理医药学杂志》2017年第7期1007-1008,共2页Journal of Mathematical Medicine

摘　　要：目的:探讨支气管哮喘急性发作患者诱导痰嗜酸性粒细胞比例变化及肺功能的关系。方法:根据随机性原则选取从2014年1月~2016年11月期间在某院住院治疗的支气管哮喘急性发作患者81例,将81例确诊为支气管哮喘急性发作患者作为临床研究对象,回顾性分析所有患者在急性发作时诱导痰嗜酸性粒细胞肺功能的关系,对其结果分析研究。结果:所有患者在出院前后FEV1/FVC和FEF25%~FEF50%的比较中,出院后FEV1/FVC和FEF25%~FEF50%的水平优于出院前FEV1/FVC和FEF25%~FEF50%的水平,差异均较为明显,具有统计学意义(P<0.05)。结论:嗜酸性粒细胞的比例增加与支气管哮喘急性发作有关,同时支气管哮喘的急性发作对肺功能有明显影响。Objective：To investigate the relationship between the changes of pharyngeal eosinophils and pulmonary function in patients with acute exacerbation of bronchial asthma.Methods：81 patients with acute exacerbation of bronchial asthma who were hospitalized from January 2014 to November 2016 were selected according to the principle of randomness.81 patients with acute exacerbation of bronchial asthma were selected as clinical research subjects.Then eetrospectively analyse all patients of the relationship of pulmonary function in the acute attack induced sputum eosinophilic and thus analyze the results.Results：FEV1/FVC and FEF25%~FEF50% after leaving hospital were significantly better than those before leaving hospital,with statistically significant difference（P〈0.05）.Conclusion：The increase of the proportion of eosinophils is related to the acute attack of bronchial asthma,and the acute attack of bronchial asthma has a significant effect on lung function.

关 键 词：支气管哮喘 急性发作 嗜酸性粒细胞 肺功能 

分 类 号：R562.25[医药卫生—呼吸系统]