基于时、频域的前额叶血氧浓度特征分析  

To Explore the Characteristics of the Blood Oxygen Concentration in the Prefrontal Lobe in Time Domain and Frequency Domain

作　　者：吴综[1] 李浩[1] 梁永波[1] 陈真诚[1] 

机构地区：[1]桂林电子科技大学,广西桂林541004

出　　处：《生物医学工程研究》2017年第2期116-120,共5页Journal Of Biomedical Engineering Research

基　　金：国家科技支撑计划项目(2013BAI03B01);国家自然科学基金资助项目(61271119);广西高等学校科学研究项目(KY2015YB096);广西物联网技术及产业化推进协同创新中心资助项目(WLW20060501)

摘　　要：本研究旨在从时域和频域两个角度出发,探究前额叶血氧浓度在任务状态下的变化特征,以及与静息状态下相比表现出的异同。随机选择21名受试者,使用多功能近红外脑功能成像仪采集每一个受试者在静息、运动想象以及运动实际发生时前额叶血氧饱和度的变化量,通过空间配准、曲线分析、配对样本t检验以及傅里叶谱分析方法对数据进行分析处理。在任务状态下,前额叶的血氧饱和度明显高于静息状态下的含量(P<0.01);运动想象状态下的血氧饱和度高于实际运动状态下的含量(P<0.05);前额叶血氧浓度变化的频率一般在0.1 Hz以下。下肢的运动想象比实际运动更能激活双侧额叶前区;血氧浓度信号变化的频率很低,通过低通滤波能有效滤除心跳和呼吸等生理活动的影响。To explore the characteristics of the blood oxygen concentration in the prefrontal lobe from time domain and frequency domain,and the similarities and differences compared with resting state. Twenty-one subjects were randomly selected. using multi-functional near infrared brain imaging instrument to monitor the changes of blood oxygen concentration in the prefrontal lobe during the subjects in states of quiet,imagination movement or actual movement,and the data were analyzed and processed by spatial registration,curve analysis,paired sample t test and fourier spectral analysis method. The blood oxygen saturation was significantly higher than the resting state in the task state（ P〈0. 01）. The oxygen saturation in the motor imagery was higher than that in the actual exercise state.（ P〈0. 05）. The frequency of changes in blood oxygen concentration in the prefrontal lobe was generally less than 0. 1 Hz. Motor imagery is more active the frontal lobe than the actual motion,and the frequency of blood oxygen signal is very low so that it can effectively filter out the effect of heart and respiration through the low pass filter.

关 键 词：大脑前额叶 氧合血红蛋白 运动想象 f NIRS 血氧饱和度 傅里叶变换 

分 类 号：R338.4[医药卫生—人体生理学]