中医药干预心肌细胞凋亡防治慢性心衰研究进展  

Experimental Research Progress of Chinese Medicine on Intervention of Myocardial Apoptosis and Prevention and Treatment of Chronic Heart Failure

作　　者：李丹[1] 王茎[2] 贾学昭 刘娜娜[1] 杨佳辉[1] 

机构地区：[1]安徽中医药大学研究生院,合肥230038 [2]安徽中医药大学中医临床学院,合肥230038

出　　处：《江西中医药大学学报》2017年第4期106-109,共4页Journal of Jiangxi University of Chinese Medicine

基　　金：国家自然科学基金项目(81574084;81273856);安徽省自然科学基金项目(1608085MH230)

摘　　要：心肌细胞凋亡是慢性心衰发生发展的重要原因之一,中医药在调控心肌细胞凋亡方面发挥着十分重要的作用,其机制可能是通过中医药的有效成分,调节细胞凋亡相关蛋白,抑制或上调凋亡蛋白的表达,从而达到减少心衰时心肌细胞凋亡,改善心功能的作用。近年来,心肌细胞凋亡与慢性心衰的关系愈发受到关注,研究中医药对心肌细胞凋亡的干预机制,以期有助于为临床治疗慢性心衰提供可靠的科学依据,更好地推动中医药事业的发展。Myocardial cell apoptosis is one of the important causes of chronic heart failure. Traditional Chinese medicine plays a very important role in the regulation of myocardial cell apoptosis. The mechanism may be through the effective ingredients of Chinese medi-cine, regulation of apoptosis related protein, by inhibiting the expression or regulation of apoptosis protein, so as to reduce myocardial apoptosis in heart failure and improve heart function. In recent years, the relationship between myocardial apoptosis and chronic heart failure are increasingly concerned about the intervention mechanism of traditional Chinese medicine on myocardial apoptosis, in order to provide reliable scientific basis for clinical treatment of chionic heart failure and to promote the development of Chinese medicine bet-ter.

关 键 词：中医药干预 心肌细胞凋亡 慢性心衰 实验研究 综述 

分 类 号：R256.2[医药卫生—中医内科学]