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机构地区:[1]广东省惠州市中心人民医院急诊内科,516000
出 处:《实用心脑肺血管病杂志》2017年第6期85-88,共4页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
摘 要:目的观察双水平气道正压(BiPAP)无创通气辅助治疗急性左心衰竭(ALHF)并低氧血症的临床效果。方法选取2013年6月—2015年12月惠州市中心人民医院收治的ALHF并低氧血症患者178例,采用随机数字表法分为A组与B组,每组89例。两组患者入院后均予以常规治疗,A组患者在常规治疗基础上予以BiPAP无创通气辅助治疗,B组患者在常规治疗基础上予以鼻导管高流量吸氧治疗。比较两组患者临床效果、治疗前和治疗后1 h、6 h动脉血氧分压(PaO_2)、血氧饱和度(SpO_2)、心率、呼吸频率,并观察两组患者治疗期间气管插管情况。结果 A组患者临床效果优于B组(P<0.05)。治疗前两组患者PaO_2、SaO_2比较,差异无统计学意义(P>0.05);治疗后1 h、6 h A组患者PaO_2、SaO_2高于B组(P<0.05)。治疗前两组患者心率、呼吸频率比较,差异无统计学意义(P>0.05);治疗后1 h、6 h A组患者心率、呼吸频率低于B组(P<0.05)。A组患者治疗期间气管插管率低于B组(P<0.05)。结论 BiPAP无创通气辅助治疗ALHF并低氧血症的临床效果确切,可有效改善患者临床症状,降低气管插管率。Objective To observe the clinical effect of bi - level positive airway pressure ( BiPAP) non - invasive ventilation in the adjuvant therapy of acute left heart failure (ALHF) complicated with hyoxemia. Methods A total of 178 ALHF patients complicated with hyoxemia were selected in the Central Peopled Hospital of Huizhou from June 2013 to December 2015, and they were divided into A group and B group according to random number table, each of 89 cases. Based on conventional treatment, patients of A group received BiPAP non - invasive ventilation for adjuvant therapy, while patients of B group received nasal catheter high - flow oxygen inhalation. Clinical effect, Pa02, Sp02, heart rate and respiratory rate before treatment, after 1 hour and 6 hours of treatment were compared between the two groups, and incidence of endotracheal intubation was observed during the treatment. Results Clinical effect of A group was statistically significantly better than that of B group (P 〈 0. 05 ). No statistically significant differences of Pa02 or Sa02 was found between the two groups before treatment ( P 〉0. 05),while Pa02 and Sa02 of A group were statistically significantly higher than those of B group after 1 hour and 6 hours of treatment ( P 〈 0. 05 ). No statistically significant differences of heart rate or respiratory rate was found between the two groups before treatment ( P 〉 0. 05 ) , while heart rate and respiratory rate of A group were statistically significantly lower than those of B group after 1 hour and 6 hours of treatment (P 〈 0. 05 ) . Incidence of endotracheal intubation of A group was statistically significantly lower than that of B group during the treatment (P 〈 0. 05 ) . Conclusion BiPAP non - invasive ventilation has certain clinical effect in the adjuvant therapy of ALHF complicated with hyoxemia, can effectively relieve the clinical symptoms and reduce the possibility of endotracheal intubation.
关 键 词:心力衰竭 心室功能 左 缺氧 双水平气道正压无创通气 治疗结果
分 类 号:R541.6[医药卫生—心血管疾病]
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