双水平气道正压无创通气辅助治疗急性左心衰竭并低氧血症的临床效果  被引量:15

Clinical Effect of Bi-level Positive Airway Pressure Non-invasive Ventilation in the Adjuvant Therapy of Acute Left Heart Failure Complicated with Hyoxemia

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作  者:谢胜[1] 王国标[1] 

机构地区:[1]广东省惠州市中心人民医院急诊内科,516000

出  处:《实用心脑肺血管病杂志》2017年第6期85-88,共4页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

摘  要:目的观察双水平气道正压(BiPAP)无创通气辅助治疗急性左心衰竭(ALHF)并低氧血症的临床效果。方法选取2013年6月—2015年12月惠州市中心人民医院收治的ALHF并低氧血症患者178例,采用随机数字表法分为A组与B组,每组89例。两组患者入院后均予以常规治疗,A组患者在常规治疗基础上予以BiPAP无创通气辅助治疗,B组患者在常规治疗基础上予以鼻导管高流量吸氧治疗。比较两组患者临床效果、治疗前和治疗后1 h、6 h动脉血氧分压(PaO_2)、血氧饱和度(SpO_2)、心率、呼吸频率,并观察两组患者治疗期间气管插管情况。结果 A组患者临床效果优于B组(P<0.05)。治疗前两组患者PaO_2、SaO_2比较,差异无统计学意义(P>0.05);治疗后1 h、6 h A组患者PaO_2、SaO_2高于B组(P<0.05)。治疗前两组患者心率、呼吸频率比较,差异无统计学意义(P>0.05);治疗后1 h、6 h A组患者心率、呼吸频率低于B组(P<0.05)。A组患者治疗期间气管插管率低于B组(P<0.05)。结论 BiPAP无创通气辅助治疗ALHF并低氧血症的临床效果确切,可有效改善患者临床症状,降低气管插管率。Objective To observe the clinical effect of bi - level positive airway pressure ( BiPAP) non - invasive ventilation in the adjuvant therapy of acute left heart failure (ALHF) complicated with hyoxemia. Methods A total of 178 ALHF patients complicated with hyoxemia were selected in the Central Peopled Hospital of Huizhou from June 2013 to December 2015, and they were divided into A group and B group according to random number table, each of 89 cases. Based on conventional treatment, patients of A group received BiPAP non - invasive ventilation for adjuvant therapy, while patients of B group received nasal catheter high - flow oxygen inhalation. Clinical effect, Pa02, Sp02, heart rate and respiratory rate before treatment, after 1 hour and 6 hours of treatment were compared between the two groups, and incidence of endotracheal intubation was observed during the treatment. Results Clinical effect of A group was statistically significantly better than that of B group (P 〈 0. 05 ). No statistically significant differences of Pa02 or Sa02 was found between the two groups before treatment ( P 〉0. 05),while Pa02 and Sa02 of A group were statistically significantly higher than those of B group after 1 hour and 6 hours of treatment ( P 〈 0. 05 ). No statistically significant differences of heart rate or respiratory rate was found between the two groups before treatment ( P 〉 0. 05 ) , while heart rate and respiratory rate of A group were statistically significantly lower than those of B group after 1 hour and 6 hours of treatment (P 〈 0. 05 ) . Incidence of endotracheal intubation of A group was statistically significantly lower than that of B group during the treatment (P 〈 0. 05 ) . Conclusion BiPAP non - invasive ventilation has certain clinical effect in the adjuvant therapy of ALHF complicated with hyoxemia, can effectively relieve the clinical symptoms and reduce the possibility of endotracheal intubation.

关 键 词:心力衰竭 心室功能  缺氧 双水平气道正压无创通气 治疗结果 

分 类 号:R541.6[医药卫生—心血管疾病]

 

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