粗叶悬钩子抗肝损伤有效成分的提取与分离  

Extraction and Separation of Effective Composition of Rubus Aleaefolius Poir. on Liver Injury

作　　者：邢奇妹 

机构地区：[1]福建中医药大学附属第三人民医院药剂科,福州350108

出　　处：《海峡药学》2017年第6期251-254,共4页Strait Pharmaceutical Journal

摘　　要：目的对粗叶悬钩子抗肝损伤有效部位的化学成分进行提取、分离。方法运用硅胶柱层析和高压制备液相色谱方法进行分离纯化,通过液质联用技术,并查阅相关文献,初步确定化合物的结构。结果分离得到6个化合物。结论围绕活性追踪,首次对粗叶悬钩子抗肝损伤有效成分进行研究。OBJECTIVE Extraction and Separation of the bioactive chemical constitutes of Rubus aleaefolius Poir. on Liver Injury. METHODS Silica gel chromatography column and preparative liquid chromatography were used for separation of compounds and HPLC-MS technique combined with relative references was used for preliminary structure determination. RESULTS Six compounds were isolated from Rubus aleaefolius Poir. CONCLUSION According to the tracing of activity bioactive chemical constitutes of Rubus aceaefolius Poir. Were firstly studied on liver injury and preparation chromatography.

关 键 词：粗叶悬钩子 有效成分 制备色谱 

分 类 号：R91[医药卫生—药学]