注射预混人胰岛素后不同时间间隔进餐对2型糖尿病患者餐后血糖谱的影响  

The influence of IMI on glucose profile in patients with T2DM injected premixed insulin

作　　者：杨胜菊[1] 

机构地区：[1]安徽省立医院内分泌科,安微合肥230001

出　　处：《川北医学院学报》2017年第3期355-357,共3页Journal of North Sichuan Medical College

基　　金：安徽省自然科学基金项目(1508085SMH227)

摘　　要：目的:分析2型糖尿病患者注射预混人胰岛素后不同的进餐时间间隔(injection-to-meal interval,IMI)对餐后血糖谱的影响。方法:选择23例2型糖尿病患者,注射预混人胰岛素后分别在第4天采用0 min、10 min、20 min、30 min的IMI,主要观察患者餐后1 h、2 h血糖值、低血糖发生率及患者更倾向何种IMI方案。结果:不同的IMI对患者的餐后血糖以及血糖波动没有显著影响,患者的低血糖发生率也没有统计学差异(P>0.05),95.65%的患者倾向于无IMI的胰岛素注射法。结论:2型糖尿病患者注射预混人胰岛素不同的IMI对餐后血糖谱无明显影响。Objective：To analyze the influence of injection-to-meal interval （IMI） on glucose profile in patients with type 2 di- abetes mellitus （T2DM） injected premixed insulin. Methods：23 patients with T2DM were randomized to the IMI 0 min, 10 rain,20 min,30 min at the 4 d after injected premixed insulin. The main observation was the blood sugar values after a meal 1 h,2 h ,the inci- dence of hypoglycemia,and what IMI program patients were more inclined to. Results：Different IMI had no significant effect on post- prandial glucose and glycemic fluctuations in patients, and there was no statistically significant difference in hypoglycemia （ P 〉 0.05 ）, and 95.65% of patients tended to have no IMI insulin injection. Conclusion：People with T2DM have no significant effect on postpran- dial blood glucose spectrum by injecting premixed insulin with different IMI.

关 键 词：糖尿病 人胰岛素注射 不同时间间隔进餐 血糖谱 

分 类 号：R587.1[医药卫生—内分泌]