元宫Cu365型与花式HCu280型宫内节育器的效果及不良反应分析  

Analysis on the effects and adverse reactions of Cu365 type IUD and HCu280 type IUD

作　　者：校林姣 李晶[1] 崔瑜[1] 李春义[1] 

机构地区：[1]十堰市太和医院,湖北医药学院附属医院妇产科,湖北十堰442000

出　　处：《中国妇幼保健》2017年第12期2709-2712,共4页Maternal and Child Health Care of China

摘　　要：目的分析元宫Cu365型与花式HCu280型宫内节育器(IUD)的效果及不良反应。方法将2013年3月-2015年2月来医院欲放置IUD的220例已婚育龄女性分为对照组(置入花式HCu280型IUD)与观察组(置入元宫Cu365型IUD),每组110例。比较随访期间两组患者IUD有效性、可接受性及不良反应发生率。结果随访过程中,共4例患者未完成随访,对照组与观察组各2例。两组随访1、3、6、12个月时累计带器妊娠、累计IUD脱落及累计IUD嵌顿发生率比较差异均无统计学意义(P>0.05);随访1、3、6个月时累计因症取出率及累计终止率比较差异均无统计学意义(P>0.05);随访12个月时累计因症取出率及累计终止率比较差异有统计学意义(P<0.05)。两组随访12个月时,观察组累计续用率(93.51%)高于对照组(83.33%),差异有统计学意义(P<0.05)。两组随访1、3个月时,子宫出血、经期延长、经量增多、白带增多发生率比较差异有统计学意义(P<0.05);随访6、12个月时,以上各指标比较差异均无统计学意义(P>0.05)。两组随访1、3、6、12个月时,疼痛发生率比较差异均无统计学意义(P>0.05)。随着随访时间的延长,有子宫内膜压迹的患者逐渐减少,但有子宫内膜瘀斑和溃疡的患者逐渐增多。随访1、3个月时,两组子宫内膜压迹发生率比较差异有统计学意义(P<0.05);随访6、12个月时,两组子宫内膜瘀斑及溃疡发生率比较差异有统计学意义(P<0.05)。两组VAS评分比较差异有统计学意义(P<0.05)。两组随访1、3个月时VAS评分比较差异有统计学意义(P<0.05);随访6、12个月时VAS评分比较差异无统计学意义(P>0.05)。结论元宫Cu365具有避孕效果稳定,可接受性高,降低子宫出血及疼痛等不良反应发生率等优点,值得临床推广应用。Objective To analyze the effects and adverse reactions of Cu365 type intrauterine device（ IUD） and HCu280 type IUD. Methods From March 2013 to February 2015,220 married women of childbearing age were selected and divided into control group（ HCu280 type IUD） and observation group（ Cu365 type IUD）,110 women in each group. The effectiveness,acceptability and incidence rates of adverse reactions during follow-up were compared between the two groups. Results Four patients didn＇t complete follow-up,including two patients in control group and two patients in observation group. There was no statistically significant difference in the incidence rate of cumulative pregnancy with IUD in situ,cumulative IUD detachment,and cumulative IUD incarceration at 1,3,6,and 12 months between the two groups（ P〉0. 05）; there was no statistically significant difference in cumulative IUD take-off rate due to symptoms and cumulative termination rate at 1,3,and 6 months between the two groups（ P〉0. 05）; there were statistically significant differences in cumulative IUD take-off rate due to symptoms and cumulative termination rate at 12 months between the two groups（ P〈0. 05）. At 12 months,the cumulative continuous rate in observation group was 93. 51%,which was statistically significantly higher than that in control group（ 83. 33%）（ P〈0. 05）. There were statistically significant differences in the incidence rates of metrorrhagia,prolonged menstruation,menorrhagia,and leukorrhagia at 1 and 3 months between the two groups（ P〈0. 05）; there was no statistically significant difference in the incidence rates of metrorrhagia,prolonged menstruation,menorrhagia,and leukorrhagia at 6 and 12 months between the two groups（ P〉0. 05）. There was no statistically significant difference in the incidence rate of pain at 1,3,6,and 12 months between the two groups（ P〉0. 05）. With the extension of follow-up time,the number of patients with endometrial impression decreased gradually,but the numbers of pa

关 键 词：宫内节育器 避孕 子宫出血 

分 类 号：R711.74[医药卫生—妇产科学]