2010-2015年广西崇左市手足口病患者病原学检测结果分析  

Etiological Analysis of Hand-Foot-Mouth Disease in Chongzuo City,Guangxi Province,2010-2015

作　　者：农晓妮 刘德平[1] 黄涛[1] 黄亚铭[2] 

机构地区：[1]崇左市疾病预防控制中心,广西崇左532200 [2]广西壮族自治区疾病预防控制中心

出　　处：《寄生虫病与感染性疾病》2017年第2期87-91,共5页Parasitoses and Infectious Diseases

摘　　要：目的分析广西崇左市手足口病病原学检测结果,为该地区今后防制提供科学依据。方法收集整理该市2010-2015年各县(市、区)送检的2 401例疑似手足口病患者的粪便、肛拭子、咽拭子、疱疹拭子标本,应用RT-PCR检测样本中肠道病毒(PE)、肠道病毒71型(EV71)、柯萨奇病毒A组16型(CoxA16)的数据。结果该市6年间共检测疑似手足口病患者标本共2 401份,核酸检测阳性1 586份,阳性率66.06%(1 586/2 401)。在1 586份患者中EV71病毒占25.03%(397/1 586);CoxA16病毒占24.78%(393/1 586);其他肠道病毒占50.19%(796/1 586)。结论该市手足口病患者EV71和CoxA16病毒隔年交替出现高峰,上半年以EV71和CoxA16患者为主,而下半年以其他肠道病毒感染患者为主。Objective To analyze etiological test results of hand-foot-mouth disease（HFMD）in Chongzuo City in Guangxi and provide a scientific basis for future prevention and control.Methods RT-PCR assay data of enterovirus（PE）,enterovirus 71（EV71）and coxsackievirus A16（CoxA16）in samples including stools,rectal swabs,throat swabs and herpes swabs of 2 401 patients with suspected HFMD delivered from each county（district）in 2010-2015 were collected and analyzed.Results A total of 2 401 samples of patients with suspected HFMD were assayed in the six years,and 1586（66.06%）gave positive results in nucleic acid test.Among the etiologies of the 1 586 cases,EV71virus accounted for 25.03%（397/1 586）,CoxA16 virus for 24.78%（393/1 586）,and other enteroviruses for 50.19%796/1 586）.Conclusion EV71 and CoxA16 viruses are responsible for HFMD peaks in different years in an alternate manner;EV71and CoxA16 account for main etiology of HFMD in the first half year,while other enteroviruses for the main etiology in the second half of each year.

关 键 词：手足口病 病原学检测 EV71 COXA16 少数民族 

分 类 号：R512.5[医药卫生—内科学]