Design and Development of PHBV/PLA Artificial Blood Vessels  

作　　者：欧阳学燕 马颜雪 朱广昌 吴琼 李毓陵 

机构地区：[1]College of Textiles,Donghua University [2]Department of Cardiovascular Thoracic Surgery,The General Hospital of the PLA Rocket Force,Beijing Normal University [3]College of Life Science,Tsinghua University

出　　处：《Journal of Donghua University(English Edition)》2017年第2期212-215,共4页东华大学学报（英文版）

基　　金："111 Project" Biomedical Textile Materials Science and Technology,China(No.B07024)

摘　　要：In the research,a β-hydroxybutyrate and β-hydroxyvalerate copolymer(PHBV)/polylactic acid(PLA)artificial blood vessel was designed and developed,and it was also implanted in vivo for a period of time to observe its biocompatibility and degradation performance.The results showed that the developed PHBV/PLA artificial blood vessel could be used to replace the natural blood vessel,but its degradation rate was too fast and the mechanical supporting force was insufficient.Thus,properties of the PHBV/PLA need to be further improved.In the research,a β-hydroxybutyrate and β-hydroxyvalerate copolymer（PHBV）/polylactic acid（PLA）artificial blood vessel was designed and developed,and it was also implanted in vivo for a period of time to observe its biocompatibility and degradation performance.The results showed that the developed PHBV/PLA artificial blood vessel could be used to replace the natural blood vessel,but its degradation rate was too fast and the mechanical supporting force was insufficient.Thus,properties of the PHBV/PLA need to be further improved.

关 键 词：β-hydroxybutyrate and β-hydroxyvalerate copolymer(PHBV)/polylactic acid(PLA) woven artificial blood vessels BIOCOMPATIBILITY degradation rate supporting force 

分 类 号：TS101.4[轻工技术与工程—纺织工程]