腹腔镜胃癌根治术可行性与安全性的Meta分析  

Feasibility and safety of laparoscopic radical gastrectomy :a Meta-analysis

作　　者：陈刚[1] 赵和照[1] 陈秀锋[1] 谭镇宗 何苗[1] 

机构地区：[1]重庆市肿瘤研究所/医院/癌症中心胃肠外科,重庆400030

出　　处：《中国现代普通外科进展》2017年第5期350-354,共5页Chinese Journal of Current Advances in General Surgery

摘　　要：目的:综合分析腹腔镜胃癌根治术与开腹胃癌根治术,探讨腹腔镜胃癌根治术的可行性和安全性。方法:计算机检索The Cochrane library、pubmed、EMbase、CBM、维普、中国知网、万方数据库,检索时间为2010年1月至2015年8月,纳入腹腔镜胃癌根治术与开腹胃癌根治术的资料,用revman5.2处理数据,评价腹腔镜胃癌根治术的可行性及安全性。结果:共纳入公开发表的7篇临床对比研究,以腹腔镜胃癌根治术为观察组,开腹胃癌根治术为对照组进行Meta分析,观察组切口长度低于对照组(MD=-12.93,95%CI:-13.16^-12.70,P<0.00001);观察组出血量更少(MD=-129.98,95%CI:-220.54^-39.42,P=0.005);观察组与对照组淋巴结清扫数目无统计学差异(MD=0.77,95%CI:-2.06~3.60,P=0.56);腹腔镜组较开腹手术时间长(MD=49.17,95%CI:25.32~73.02,P<0.0001);观察组住院时间较对照组短(MD=-2.27,95%CI:-3.77^-0.77,P=0.003)。结论:腹腔镜胃癌根治术治疗胃癌是可行的,在手术彻底性、微创及安全性方面优于开腹胃癌根治术。Objective： To explore the feasibility and safety of laparoscopic radical gastrectomy for gastric cancer through analysising the laparoscopic radical gastrectomy and open radical gastrec- tomy. Methods： Retrieval the Cochrane Library, PubMed, EMBASE, CBM, VIP, CNKI, WANFANG DATA, the time is from January 2010 to August 2015. Bring into the comparative studies about la-parosopic radical gastrectomy and laparotomye.Processing data using the revman 5.2 to reaserch the feasibility and safety of laparoscopic radical gastrectomy. Results： 7 clinical comparative stud- ies were included in this study. The observation group was the group of laparoscopic radical gas- trectomy and the control group was the group of laparotomye. Results showed that the length of in- cision of the observation group was shorterfM D=- 12.93, 95% CI （- 13.16, - 12.70）, P〈0.00001]; The observation group bleeding was lesser[MD=-129.98, 95%C1（-220.54, -39.42）, P=0.005]; The num- ber of lymph node of the two groups had no significant difference [MD=0.77, 95% Cl （-2.56, 3.60）, P=0.56];The operation time of the observation group was longer [MD=49.17, 95% CI （25.32, 73.02）, P〈0.0001]; The hospitalization time of the observation group is shorter [MD=-2.27, 95% C1（-3.77, 0.77）, P=0.003]. Conclusion： Laparoscopic radical gastrectomy is feasible and it is superior to la- parotomye within the thoroughness, minimally invasiving and safety.

关 键 词：腹腔镜 胃癌根治术 META分析 

分 类 号：R735.2[医药卫生—肿瘤]