机构地区:[1]浙江中医药大学附属第三医院针灸科,杭州310005 [2]浙江中医药大学第三临床医学院 [3]浙江中医药大学附属第三医院脾胃科
出 处:《中国针灸》2017年第7期717-721,共5页Chinese Acupuncture & Moxibustion
基 金:国家中医药管理局全国名老中医药专家传承工作室建设项目(方剑乔全国名老中医药专家传承工作室):国中医药人教发[2013]47号;浙江省名老中医专家传承工作室建设计划(浙江省方剑乔名老中医专家传承工作室):GZS2012014;第二期(2015年度)浙江省医坛新秀人才培养计划:[浙卫发(2015)70号]
摘 要:目的:比较简易穴位埋线法与药物口服治疗女性功能性便秘的临床疗效差异。方法:将56例女性功能性便秘患者按照1:1比例随机分为埋线组和西药组,剔除脱落病例8例,最终埋线组22例,西药组26例。埋线组予简易穴位埋线法治疗,以腹四穴(中脘、天枢、关元)为主穴,配以下脘、滑肉门、外陵、支沟、上巨虚穴,每周1次;西药组予乳果糖口服,每日3次,治疗周期均为8周。主要疗效指标为治疗后6周期间平均每周完全排净感的自主排便次数(CSBMs)较治疗前增加2次的病例数所占的百分比;并比较治疗前后及12周随访各次要疗效指标,包括周平均CSBM及其增加次数、便秘患者生活质量量表(PAC-QOL)、Bristol大便性状积分和排便困难程度评分。结果:埋线组周平均CSBM增加2次的百分比明显高于西药组(P<0.05);与本组治疗前比较,两组患者治疗后周平均CSBM次数增加(均P<0.01),Bristol大便性状积分改善(均P<0.01),PAC-QOL量表评分、排便困难程度评分均降低(均P<0.01);埋线组周平均CSBM增加次数较西药组明显偏多(P<0.01),PAC-QOL量表评分明显优于西药组(P<0.01),Bristol大便性状和排便困难程度均优于西药组(P<0.05)。结论:简易穴位埋线可以明显增加女性功能性便秘患者的CSBM,改善Bristol大便性状和排便困难程度,提高其生活质量。Objective To compare the effects between acupoint embedding and oral medication for female functional constipation. Methods Fifty-six female patients were randomized into an embedding group and a medication group(1:1).There were 22 cases in the embedding group and 26 cases in the medication group with total 8 patients dropped out. The main embedding acupoints were Zhongwan(CV 12), bilateral Tianshu(ST 25) and Guanyuan(CV 4), combined with Xiawan(CV 10), Huaroumen(ST 24), Wailing(ST 26), Zhigou(TE 6) and Shangjuxu(ST 37). It was given once a week. Oral lactulose was applied in the medication group, 3 times a day. The treatment cycle was 8 weeks. The primary outcome was the percentage of patients whose weekly average number of complete spontaneous bowel movement(CSBM) was increased ≥2 compared with baseline during the last 6 weeks in the treatment period. The secondary efficacy indices were compared before and after treatment as well as at follow-up at the 12 th week, including the weekly average number and increased number of CSBM, the quality of life of patients with constipation(PAC-QOL), the Bristol stool character score, and the assessment of difficulty in defecation. Results The percentage of patients whose weekly average number of CSBMs were increased ≥2 in the embedding group significantly increased compared with that in the medication group(P〈0.05). The weekly average number of CSBM in the two groups increased after treatment compared with those before treatment(both P〈0.01); the score of Bristol stool character improved(both P〈0.01); the scores of PAC-QOL and difficulty in defecation decreased(all P〈0.01).The increasing time of weekly average CSBM in the embedding group was higher than that in the medication group(P〈0.01);the score of PAC-QOL in the embedding group after treatment was better than that in the medication group(P〈0.01); the Bristol stool character and difficulty degree in the embedding group after treatment
分 类 号:R246.1[医药卫生—针灸推拿学]
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