美托洛尔联合地尔硫卓对冠心病不稳定型心绞痛患者的疗效观察  

Metoprolol combining diltiazem for patients with coronary heart disease with unstable angina pectoris

作　　者：李琳[1] 秦保健 Li Lin Qin Baojian(Central Hospital of Shanxian County, Heze 274300, Chin)

机构地区：[1]单县中心医院,菏泽274300

出　　处：《国际医药卫生导报》2017年第13期2073-2074,共2页International Medicine and Health Guidance News

摘　　要：目的研究美托洛尔联合地尔硫卓对冠心病不稳定型心绞痛患者的疗效观察。方法选取本院治疗冠心病不稳定型心绞痛患者78例，随机数字表法分组，各39例。对照组予以美托洛尔治疗，观察组予以美托洛尔联合地尔硫卓治疗。两组临床治疗有效率比较，检测两组治疗前后心功能指标左心射血分数（LVEF）情况比较。结果观察组临床治疗总有效率为94．87％，明显高于对照组76．92％，差异有统计学意义（χ2=5．186，P〈O．05）；治疗后观察组LVEF值高于对照组，差异有统计学意义（P〈0．05）。结论美托洛尔联合地尔硫卓治疗冠心病不稳定型心绞痛，可改善患者心脏功能，临床效果显著。Objective To study the effect of metoprolol combining diltiazem for patients with coronary heart disease with unstable angina pectoris. Methods 78 patients with coronary heart disease with unstable angina pectoris treated at our hospital were selected and randomly divided into a control group and an observation group, 39 cases for each group. The control group were treated with metoprolol and the observation group metoprolol and diltiazem. The clinical efficacies were compared between these two groups. The cardiac function [left ventricular ejection fraction （LVEF）] in both groups was measured before and after treatment. Results The total effective rate was 94.87% in the observation group and was 76.92% in the control group, with a statistical difference （χ2=5-186, P〈0.05）. After treatment, the LVEF was higher in the observation group than in the control group, with a statistical difference （P〈0.05）. Conclusions Metoprolol combining diltiazem for patients with coronary heart disease with unstable angina pectoris can improve the patients＇ cardiac function and is clinically and significantly effective.

关 键 词：地尔硫卓 美托洛尔 冠心病不稳定型心绞痛 

分 类 号：R541.4[医药卫生—心血管疾病]