桃红清血丸及卤米松乳膏联合窄波紫外线治疗白癜风的临床效果  

Clinical effect of Taohong Qingxue pill and Halometasone cream combined with narrow-band UVB in the treatment of vitiligo

作　　者：解士海[1] 赵卫华[1] 黄壮峰 张国平[1] 

机构地区：[1]惠州市皮肤病防治研究所皮肤科,516001

出　　处：《国际医药卫生导报》2017年第14期2209-2212,共4页International Medicine and Health Guidance News

摘　　要：目的探讨桃红清血丸、卤米松乳膏联合窄谱中波紫外线（Narrow—bandUVB，NB—UVB）治疗白癜风（Vitiligo）的临床效果。方法选择2015年1月至2016年10月期间本研究所收治的自癜风患者102例，按照数字表法随机分为3组，对照组35例给予外用卤米松乳膏治疗；观察B组34例在对照组基础上加用桃红清血丸治疗；观察A组33例在观察组B组基础上给予窄谱中波紫外线治疗，并比较3组的临床效果。结果经治疗12周后，观察A组总有效率（96．97％）显著高于对照组的60．00％及观察B组的79．41％（x2=13．5025、4．9099，P〈0．05），而观察B组总有效率明显高于对照组（x2=3．0695，P〈0．05）；3组均未发现不良反应，均无肝肾功能异常。结论白癜风（Vitiligo）患者应用桃红清血丸、卤米松乳膏联合窄谱中波紫外线（NB—UVB）治疗配合优质综合护理临床效果显著，不良反应发生率低，值得临床大力推广应用。Objective To study the clinical effect of Taohong Qingxue pill and Halometasone cream combined with narrow-band UVB （NB-UVB） in the treatment of vitiligo. Methods A total of 102 patients with vitiligo were enrolled in our institute from January 2015 to October 2016. They were randomly divided into three groups according to the digital table method. 35 cases in the control group were treated with external Halometasone cream, 34 cases in the observation group B were treated with Taohong Qingxue pill on the basis of the control group, 33 cases in the observation group A were treated with NB-UVB on the basis of the observation group B. The clinical effect of the three groups were compared. Results After 12 weeks of treatment, the total effective rate in observation group A （96.97%） was significantly higher those in control group （60.00%） and observation group B （79.41%） （X 2=13.502 5, 4.909 9, P〈0.05）, and the total effective rate in observation group B was significantly higher than that in control group （X 2=3.069 5, P〈0.05）. There were no adverse reactions in 3 groups, no liver and kidney dysfunction. Conclusion The patients with vitiligo treated with Taohong Qingxue pill and Halometasone cream combined with NB-UVB in combination with high-quality comprehensive nursing have significant clinical effect, with low incidence of adverse reactions, worthy of clinical application.

关 键 词：白癜风 卤米松乳膏 桃红清血丸 窄谱中波紫外线 

分 类 号：R758.41[医药卫生—皮肤病学与性病学]