原发性皮肤淀粉样变皮肤镜特征分析  

Dermoscopic features of primary cutaneous amyloidosis

作　　者：罗毅鑫[1] 刘洁[1] 池城 王诗琪[1] 渠涛[1] 刘跃华[1] 晋红中[1] Luo Yixin Liu Jie Chi Cheng Wang Shiqi Qu Tao Liu Yuehua Jin Hongzhong(Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beifing 100730, China)

机构地区：[1]中国医学科学院北京协和医学院北京协和医院皮肤科,北京100730

出　　处：《中华皮肤科杂志》2017年第7期478-481,共4页Chinese Journal of Dermatology

基　　金：米尔斯坦亚美医学基金会-皮肤病研究基金

摘　　要：目的 描述原发性皮肤淀粉样变的常见皮肤镜特征，探讨皮肤镜在原发性皮肤淀粉样变辅助诊断中的应用价值。方法 收集2014年4月至2016年12月在北京协和医院皮肤科门诊就诊并行皮肤镜检查的原发性皮肤淀粉样变患者17例，分析45处皮损的皮肤镜特征。结果 原发性皮肤淀粉样变常见的皮肤镜特征为存在中心区域（可为白色、棕色或瘢痕样结构）和多种形态的色素结构及亮白色条纹。45处皮损（100%）皮肤镜下均观察到中心区域。14处（31%）苔藓样皮损仅有白色中心区域，5处（11%）苔藓样皮损同时具有白色中心区域和瘢痕样结构。8处（18%）斑状皮损仅有棕色中心区域，6处（13%）苔藓样皮损和17处（38%）斑状皮损同时具有白色及棕色中心区域。所有皮损均有多种形态的色素结构。4处（9%）苔藓样皮损有亮白色条纹。结论 皮肤镜在原发性皮肤淀粉样变的辅助诊断中具有良好的应用价值。Objective To describe common dermoscopic features of primary cutaneous amyloidosis （PCA）, and to explore the application value of dermoscopy in assisting the diagnosis of PCA. Methods Seventeen patients with PCA were collected from Department of Dermatology of Peking Union Medical College Hospital between April 2014 and December 2016. A total of 45 skin lesions were subjected to dermoscopy, and their dermoscopic features were analyzed. Results The common dermoscopic features of PCA included central hubs, which could be white, brown or scar？like areas, various pigment structures and shiny white streaks. Dermoscopy showed that central hubs could be observed in all the lesions （100%）, while white center hubs alone were observed in 14 （31%） lichenoid lesions, both white center hubs and scar？like areas in 5 （11%） lichenoid lesions, brown center hubs alone in 8 （18%） macular lesions, both white and brown center hubs in 6 （13%） lichenoid lesions and 17 （38%） macular lesions. All the lesions showed various pigment structures. Shiny white streaks were observed in 4 （9%） lichenoid lesions. Conclusion Dermoscopy has good application value in assisting the diagnosis of PCA.

关 键 词：淀粉样变性 皮肤镜检查 病理过程 原发性皮肤淀粉样变 

分 类 号：R758.6[医药卫生—皮肤病学与性病学]