三氟甲磺酸酯的高效合成（英文）  

A Practical Synthesis of Trifluoromethanesulfonate Esters

作　　者：郑东青[1,2] 马海燕[2] 丁凯[1] 

机构地区：[1]中国科学院上海有机化学研究所天然产物合成有机化学重点实验室,上海200032 [2]华东理工大学化学系,上海200237

出　　处：《有机化学》2017年第6期1582-1584,共3页Chinese Journal of Organic Chemistry

基　　金：supported by the National Natural Science Foundation of China(No.20902098)~~

摘　　要：原甲酸酯与三氟甲磺酸酐反应可高效合成三氟甲磺酸酯.该方法具有无需溶剂,反应条件温和,反应时间短,高产率,操作简单,底物范围广的特点.原位产生的试剂具有高的反应活性,可一锅法高产率制备三氟甲磺酸离子液体.A practical synthesis of trifluoromethanesulfonate esters by reaction of orthoformate esters with triflic anhydride is described. The solvent-free method featured mild condition, short time, high yield, simple operation and broad substrate scope. The in situ generated trifluoromethanesulfonate ester is highly reactive alkylating agent, providing triflate ionic liquid in excellent yield via a one-pot procedure.

关 键 词：三氟甲磺酸酯 原酸酯 三氟甲磺酸酐 一锅法烷基化 

分 类 号：O623.84[理学—有机化学]