采用电感耦合等离子质谱法检测水蛭药材中重金属的含量  

Heavy metal measurement in leeches with inductively coupled plasma mass spectrometry

作　　者：李红霞[1] 王文祎 徐国杰[1] 徐清[1] 张帆[1] 刘春生[1] 杨瑶珺[1] LI Hongxia WANG Wenyi XU Goujie XU Qing ZHANG Fan LIU Chunshen YANG Yaojun(School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 100102, China)

机构地区：[1]北京中医药大学中药学院,北京100102

出　　处：《北京中医药大学学报》2017年第6期498-502,共5页Journal of Beijing University of Traditional Chinese Medicine

基　　金：国家中医药管理局2015年度中医药行业科研专项(No.2015468002-2)~~

摘　　要：目的检测水蛭药材中重金属的含量,为保障水蛭药材安全用药提供依据。方法采用电感耦合等离子质谱(ICP-MS)技术,检测不同产地、不同部位水蛭药材中6种重金属的含量。结果不同产地水蛭药材中汞、铅和镉3种元素的含量基本符合国家现行标准规定,部分砷元素超出国家有关现行标准。但是不同产地水蛭药材中铜和铬2种元素的含量均超出国家现行有关标准。水蛭药材不同部位中重金属的含量存在明显的差异性,在头部最少,中部次之,尾部最多。结论水蛭药材中各重金属含量存在明显的产地、部位差异性,研究结果能够为保障水蛭药材的质量和用药安全提供重要参考依据。Objective To measure the content of trace heavy metal in the medicinal leech and provide references for quality control.Methods In this study, inductively coupled plasma mass spectrometry （ICP-MS） was used to determine the content of 6 heavy metal elements in different parts of the medicinal leeches from various places of origin.Results Content of mercury, lead and cadmium of leeches from different habitats met the current national standards, arsenic in some samples is beyond the current national standard, while the content of cuprum and chromium in medicinal leeches exceeded the current national standards.There were significant differences in trace heavy metal amount in different parts of the leeches.Most heavy metal accumulated at tail, some at middle part, and less at head.Conclusion The results suggest there are significant differences in heavy mental content among medicinal leeches from different places of origin and different parts of leeches.This study provides important references for quality control of medicinal leeches.

关 键 词：水蛭 电感耦合等离子质谱 重金属 

分 类 号：R284.2[医药卫生—中药学]