176例突发性聋患者血液学指标分析  

The analysis of hematologic parameters of 176 cases of sudden deafness

作　　者：周长明[1] 韩淼[1] 杨川[1] 张转[1] 王翠翠[1] 刘涛[1] 

机构地区：[1]延安大学附属医院耳鼻咽喉科,陕西延安716000

出　　处：《延安大学学报（医学科学版）》2017年第2期25-27,30,共4页Journal of Yan'an University:Medical Science Edition

基　　金：陕西省科学技术研究发展计划项目(2013K14-02-27);延安市耳鼻咽喉头颈临床研究科技创新团队(2015CXTD-10)

摘　　要：目的探讨突发性聋患者的血液学指标与突发性聋发生的关系。方法回顾性分析176例突聋患者与60例健听对照者的血液学指标。结果突聋组与对照组相比,在血小板(PLT)、总蛋白(TP)、白蛋白(Alb)、载脂蛋白B(apo-B)及白细胞计数方面差异具有统计学意义(P<0.05);血糖、在血流变学及凝血状态(全血粘度高切和低切、Ⅷ:C、VWF、AT-Ⅲ、PLG、Fg及α2-AP)、血脂(极低密度脂蛋白VLDL、脂蛋白A(LPA)、总胆固醇TC、甘油三酯TG)、空腹血糖(FBC)、血钾(K+)和白细胞及中性粒细胞百分比方面差异具有显著统计学意义(P<0.01)。结论突聋的发生可能与血脂异常、血糖升高、血粘度增高、血钾偏低、肝功异常、凝血活性增强及白细胞水平改变有关。Objective To discuss the relationship between people with sudden deafness and some hematologic parameters. Methods The hematologic parameters of 176 cases with sudden deafness and 60 cases healthy people were analyzed retrospectively. Results There were differences in blood platelet,total protein,albumin,apolipoprotein-B and white blood count between normal groups and the hearing loss groups. There were significant differences in blood glucose,blood stream state（ such as apolipoprotein A,total cholesterol,triglycerides,very low density lipoprotein cholesterol）,blood lipids,serum kalium,fasting glucose and the percent of neutrophile granulocyte between normal groups and the hearing loss groups. Conclusion The sudden deafness was related to blood stream state,abnormal liver function,dyslipidemia,hyperglycemia,hypokalemia and white blood count.

关 键 词：突发性聋 血液学指标 危险因素 

分 类 号：R764.43[医药卫生—耳鼻咽喉科]