软肝煎加减方联合药膳治疗肝硬化腹水合并营养不良临床研究  

Clinical Study of Modified Ruangan Jian Combined with Medicated Diet for Cirrhosis Ascites and Malnutrition

作　　者：陈凯生 刘铭 魏卓红[3] 

机构地区：[1]潮州市湘桥区中医医院,广东潮州521021 [2]潮州市潮州医院,广东潮州521011 [3]潮州市中心医院,广东潮州521021

出　　处：《新中医》2017年第7期58-60,共3页New Chinese Medicine

基　　金：潮州市卫生计生局科研项目(潮卫科研201485号)

摘　　要：目的:观察在常规治疗基础上加用软肝煎联合药膳治疗肝硬化腹水合并营养不良的临床效果。方法:选取80例脾肾阳虚型肝硬化腹水合并营养不良患者,随机分为对照组与观察组各40例,2组均给予护肝、利尿、补充白蛋白等常规治疗,观察组加用软肝煎联合药膳治疗,2组均以4周为1疗程,治疗3疗程。对比2组的临床疗效,治疗前后检测患者的体质量指数(BMI)、三头肌皮褶厚度(TSF)、上臂围(AC)、血清白蛋白(Alb)、前白蛋白(PA)、凝血酶原活动度(PTA),观察记录腹胀、黄疸、无力、下肢浮肿、少尿、纳呆等症状的消失时间。结果:观察组愈显率高于对照组,差异有统计学意义(P<0.05)。2组BMI、TSF及AC治疗前后比较,差异均无统计学意义(P>0.05)。2组Alb、PA、PTA均较治疗前升高(P<0.05),观察组3项指标值均高于对照组,差异均有统计学意义(P<0.05)。观察组腹胀、黄疸、无力、下肢浮肿、少尿、纳呆消失时间均较对照组缩短,差异均有统计学意义(P<0.05)。结论:在常规治疗基础上加用软肝煎联合药膳治疗肝硬化腹水合并营养不良临床效果显著,能够有效缓解患者的临床症状,提高肝脏合成功能,虽未能明显提高人体测量指标,但改善了能够反映人体营养状态的指标。Objective：To observe the clinical effect of Ruangan jian combined with medicated diet on the basis of routine treatment for cirrhosis ascites and malnutrition. Methods ：Divided 80 cases of patients with cirrhosis ascites and malnutrition of spleen-kidney yang deficiency type into the control group and the observation group randomly,40 cases in each group.Both groups were treated with liver protection, diuresis, albumin supplement and other routine treatment, while the observation group was additionally treated with Ruangan jian combined with medicated diet. Both groups received treatment of4 weeks for one course,three courses in total. Compared the clinical effect,and determined body mass index（BMI）,triceps skinfold（TSF）, arm circumference（AC）, serum albumin（Alb）, prealbumin（PA） and prothrombin activity（PTA） in both groups.Observed and recorded the disappearance time of symptoms such as abdominal distension,jaundice,asthenia,lower limb edema,oliguria and anorexia. Results ：The cured and markedly effective rate in the observation group was higher than that in the control group（P〈0.05）. Compared BMI,TSF and AC in both groups before and after treatment,there was no significance in differences（P〉0.05）. Alb, PA, PTA in both groups after treatment were increased when compared with those before treatment, and the three indexes in the observation group were all higher than those in the control group（P〈0.05）. The disappearance time of abdominal distension,jaundice,asthenia,lower limb edema,oliguria and anorexia in the observation group were shorter than that in the control group（P〈0.05）. Conclusion：The therapy of Ruangan jian combined with medicateddiet on the basis of routine treatment for cirrhosis ascites and malnutrition has significant curative effect. It can effectively relieve clinical symptoms and enhance liver synthesis function. Although it has not obviously increased anthropometric parameters,but it has improved indexes that can reflect body condition of n

关 键 词：肝硬化腹水 营养不良 慢性乙型病毒性肝炎 脾肾阳虚型 中西医结合疗法 软肝煎 药膳 肝功能 

分 类 号：R657.31[医药卫生—外科学]